Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330742 | 0.98 | MMP8 (0.37) | MMP8MMP2MMP1MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL3930213 | 0.87 | FDPS (0.32) | MMP8MMP2MMP1MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL2264607 | 0.87 | MMP2 (0.37) | MMP8MMP2MMP1MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL2261291 | 0.85 | ANPEP (0.39) | — | |
| Hydrochloric Acid SCHEMBL1227055 | 0.84 | ACP3 (0.34) | MMP8MMP2MMP1MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL2259936 | 0.83 | MMP2 (0.39) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL1226946 | 0.82 | ACP3 (0.35) | MMP8MMP2MMP1MMP3MMP7 | |
| Hydrochloric Acid SCHEMBL6446792 | 0.81 | RAB9A (0.38) | LMNAKDM4EALDH1A1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2262115 | 0.81 | MMP2 (0.41) | MMP8MMP2MMP14CA1CA9 | |
| Bromide SCHEMBL1227449 | 0.81 | LMNA (0.36) | MMP8MMP2MMP1MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090259042-A1 | ELECTROCHROMIC COMPOUNDS | NTERA LIMITED (IE) | 2009-10-15 | — | — | US | claimed |
| US-20060110638-A1 | Electrochromic compounds | NTERA LIMITED (IE) | 2006-05-25 | — | — | US | claimed |
| EP-1443091-A1 | Electrochromic compounds | Ntera Limited (IE) | 2004-08-04 | — | — | EP | claimed |
| US-8999430-B2 | Method of manufacturing display element | KONICA MINOLTA HOLDINGS, INC. (JP) | 2015-04-07 | — | — | US | disclosed |
| EP-2149816-B1 | METHOD OF MANUFACTURING AN ELECTROCHROMIC DISPLAY ELEMENT | KONICA MINOLTA HOLDINGS INC (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-8014056-B2 | Display element and method of driving the same | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-8004742-B2 | Electrochromic display device | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-08-23 | — | — | US | disclosed |
| US-20100166946-A1 | METHOD OF MANUFACTURING DISPLAY ELEMENT | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-07-01 | — | — | US | disclosed |
| US-20100091353-A1 | DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-04-15 | — | — | US | disclosed |
| EP-2149816-A1 | METHOD FOR PRODUCTION OF DISPLAY ELEMENT | Konica Minolta Holdings, Inc. (JP) | 2010-02-03 | — | — | EP | disclosed |
| US-20090316249-A1 | ELECTROCHROMIC DISPLAY DEVICE | KONICA MINOLTA HOLDINGS, INC. (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090259042-A1 | ELECTROCHROMIC COMPOUNDS | NTERA LIMITED (IE) | 2009-10-15 | — | — | US | disclosed |
| US-7567371-B2 | Electrochromic compounds | NTERA LIMITED (IE) | 2009-07-28 | — | — | US | disclosed |
| EP-2040115-A1 | ELECTROCHROMIC DISPLAY DEVICE | Konica Minolta Holdings, Inc. (JP) | 2009-03-25 | — | — | EP | disclosed |
| US-20060110638-A1 | Electrochromic compounds | NTERA LIMITED (IE) | 2006-05-25 | — | — | US | disclosed |
| EP-1443091-A1 | Electrochromic compounds | Ntera Limited (IE) | 2004-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259042-A1 | ELECTROCHROMIC COMPOUNDS | ETV6, HCN2, EED | ACHE 161/4885MMP8 2139/4885MMP2 2943/4885 |
| US-20060110638-A1 | Electrochromic compounds | ETV6, HCN2, EED | ACHE 161/4885MMP8 2139/4885MMP2 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.