SCHEMBL2270587

SCHEMBL2270587

O=C(Nc1cc(CCc2ccccc2)ccc1C(=O)O)c1cc(F)cc(F)c1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTC4S Q16873 1/20 0.48
MEN1 O00255 2/20 0.48
PKM P14618 2/20 0.48
KMT2A Q03164 2/20 0.48
MAPT P10636 1/20 0.48
GRIK1 P39086 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
PLK1 P53350 7/20 0.47
PLK3 Q9H4B4 5/20 0.47
MCL1 Q07820 1/20 0.47
BCL2A1 Q16548 1/20 0.47
ACLY P53396 3/20 0.47
HCAR2 Q8TDS4 2/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA4 P22748 1/20 0.45
CA7 P43166 1/20 0.45
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2275745 0.90 NPC1 (0.56) LTC4SMEN1PKMKMT2AMAPT
SCHEMBL2271933 0.90 MEN1 (0.54) LTC4SMEN1PKMKMT2AMAPT
SCHEMBL2270145 0.90 KMT2A (0.55) LTC4SMEN1PKMKMT2AMAPT
SCHEMBL2271080 0.88 MEN1 (0.56) LTC4SMEN1PKMKMT2AMAPT
SCHEMBL2275929 0.88 KMT2A (0.62) LTC4SMEN1PKMKMT2AMAPT
SCHEMBL2276254 0.85 CA12 (0.48) LTC4SMEN1PKMKMT2AMAPT
SCHEMBL2274146 0.85 PLK1 (0.56) LTC4SMEN1PKMKMT2AMAPT
SCHEMBL2271168 0.85 ACLY (0.67) LTC4SMEN1PKMKMT2AMAPT
SCHEMBL2273479 0.85 NPC1 (0.53) LTC4SMEN1PKMKMT2AGRIK1
SCHEMBL2270705 0.84 ACLY (0.59) LTC4SMEN1PKMKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7999132-B2 Anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2011-08-16 US disclosed
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-09-24 US disclosed
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF MMP13, MMP26, MMP11 LTC4S 2518/4885MEN1 3105/4885PKM 2367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.