Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2265910 | 0.84 | MAPT (0.50) | ABCG2MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL2267169 | 0.78 | NPY5R (0.44) | ABCG2RETMEN1KMT2AMAPT | |
| SCHEMBL10374649 | 0.78 | MAPT (0.43) | KMT2AMAPTGAAPOLBHSD17B10 | |
| SCHEMBL10374650 | 0.78 | PIK3CD (0.38) | MEN1KMT2AMAPTNPSR1EGFR | |
| SCHEMBL10650908 | 0.77 | MEN1 (0.49) | ABCG2MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6811822 | 0.76 | ALDH1A1 (0.45) | ABCG2RETVSIRBRAFMEN1 | |
| SCHEMBL8043904 | 0.75 | NNMT (0.35) | RETMAPTHSD17B10MAPK1LMNA | |
| SCHEMBL95212 | 0.72 | SIRT2 (0.41) | KMT2APOLBHSD17B10MAPK1LMNA | |
| SCHEMBL29378197 | 0.72 | SIRT2 (0.41) | KMT2APOLBHSD17B10MAPK1LMNA | |
| SCHEMBL2947601 | 0.71 | NR4A1 (0.56) | ABCG2MEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1586303-A1 | Dye composition comprising at least one diaminopyrazole as oxidation base and at least one 6-alkoxy-2,3-diaminopyridine as coupler | L'OREAL (FR) | 2005-10-19 | — | — | EP | claimed |
| EP-1586302-A1 | Dye composition comprising at least one pyrazolopyrimidine as oxidation base and at least one 6-alkoxy-2,3-diaminopyridine as coupler | L'OREAL (FR) | 2005-10-19 | — | — | EP | claimed |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | L'OREAL (FR) | 2004-11-25 | — | — | US | claimed |
| EP-1457198-A1 | Dyeing composition comprising at least one diaminopyrazole precursor and at least one 6-alcoxy 2,3-diaminopyridine coupler | L'OREAL (FR) | 2004-09-15 | — | — | EP | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1413286-A1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | L'OREAL (FR) | 2004-04-28 | — | — | EP | claimed |
| EP-1405628-A1 | Dyeing composition comprising at least one pyrazolopyrimidine oxidation base and at least one 6-alkoxy-2,3-diaminopyrimidine coupler | L'OREAL (FR) | 2004-04-07 | — | — | EP | claimed |
| US-20020170122-A9 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | L'OREAL S.A. (FR) | 2002-11-21 | — | — | US | claimed |
| US-20020013973-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | PLOS GREGORY (FR) | 2002-02-07 | — | — | US | claimed |
| EP-1138318-A2 | Composition for oxidative dyeing of keratinous fibres and dyeing process using same | L'OREAL (FR) | 2001-10-04 | — | — | EP | claimed |
| EP-2182914-B1 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'ORÉAL (FR) | 2017-11-08 | — | — | EP | disclosed |
| EP-2175830-B1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | ORÉAL L (FR) | 2015-09-30 | — | — | EP | disclosed |
| US-8043385-B2 | Composition oxidation colouring of keratinic fibres, containing a cationic cellulose ether, a metasilicate and oxidation dyes, method for oxidation colouring and uses thereof | L'OREAL S.A. (FR) | 2011-10-25 | — | — | US | disclosed |
| US-8002847-B2 | Composition for oxidation dyeing keratin fibres comprising a cationic cellulose ether, a weakly oxyethylenated sorbitan fatty acid ester and oxidation dyes | L 'OREAL S.A. (FR) | 2011-08-23 | — | — | US | disclosed |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | L'OREAL S.A. (FR) | 2010-11-04 | — | — | US | disclosed |
| EP-1413286-A1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | L'OREAL (FR) | 2004-04-28 | — | — | EP | disclosed |
| EP-1405628-A1 | Dyeing composition comprising at least one pyrazolopyrimidine oxidation base and at least one 6-alkoxy-2,3-diaminopyrimidine coupler | L'OREAL (FR) | 2004-04-07 | — | — | EP | disclosed |
| US-20020170122-A9 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | L'OREAL S.A. (FR) | 2002-11-21 | — | — | US | disclosed |
| US-20020013973-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | PLOS GREGORY (FR) | 2002-02-07 | — | — | US | disclosed |
| EP-1138318-A2 | Composition for oxidative dyeing of keratinous fibres and dyeing process using same | L'OREAL (FR) | 2001-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013973-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | KRT18, PPOX, AOX1 | ABCG2 2986/4885RET 2162/4885VSIR 4304/4885 |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | KRT18, KRTCAP2, FASN | ABCG2 2627/4885RET 3680/4885VSIR 2443/4885 |
| US-20020170122-A9 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods | KRT18, PPOX, AOX1 | ABCG2 2986/4885RET 2162/4885VSIR 4304/4885 |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | KRT18, CDC73, PYCR1 | ABCG2 2546/4885RET 1190/4885VSIR 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.