SCHEMBL2271985

SCHEMBL2271985

CCCC[SiH](C=CCl)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.32
PCSK9 Q8NBP7 1/20 0.32
PTGS2 P35354 1/20 0.31
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2273446 0.79 SIGMAR1 (0.32) LTA4HPCSK9SIGMAR1
SCHEMBL2267192 0.79 GAA (0.33) LTA4HPCSK9SIGMAR1
SCHEMBL2267452 0.77 SIGMAR1 (0.31) SIGMAR1
SCHEMBL2273123 0.77 KCNH2 (0.33)
SCHEMBL8992356 0.77 PTGS2 (0.36) LTA4HPCSK9PTGS2LMNASMN1; SMN2
SCHEMBL16210098 0.74 SOAT2 (0.42) LMNA
SCHEMBL16209643 0.74 SOAT2 (0.42) LMNA
SCHEMBL16210097 0.74 SOAT2 (0.42) LMNA
SCHEMBL16209644 0.74 SOAT2 (0.42) LMNA
SCHEMBL704628 0.72 LTA4H (0.35) LTA4HPCSK9PTGS2SMN1; SMN2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed