SCHEMBL2267192

SCHEMBL2267192

CCCC[SiH](C=CN(C)C)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
ALOX12 P18054 1/20 0.33
CRHBP P24387 1/20 0.33
HTT P42858 1/20 0.33
CRHR2 Q13324 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RECQL P46063 1/20 0.33
SIGMAR1 Q99720 2/20 0.32
OPRM1 P35372 2/20 0.31
OPRL1 P41146 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
KCNH2 Q12809 1/20 0.30
PCSK9 Q8NBP7 1/20 0.30
LTA4H P09960 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2273123 0.85 KCNH2 (0.33) TDP1KCNH2
SCHEMBL2271985 0.79 LTA4H (0.32) SIGMAR1PCSK9LTA4H
SCHEMBL2273446 0.76 SIGMAR1 (0.32) GAAMAPTALOX12CRHBPHTT
SCHEMBL2267452 0.75 SIGMAR1 (0.31) SIGMAR1
SCHEMBL8992356 0.74 PTGS2 (0.36) SIGMAR1TDP1PCSK9LTA4H
SCHEMBL16210098 0.71 SOAT2 (0.42) MAPTTDP1
SCHEMBL16209644 0.71 SOAT2 (0.42) MAPTTDP1
SCHEMBL16209643 0.71 SOAT2 (0.42) MAPTTDP1
SCHEMBL16210097 0.71 SOAT2 (0.42) MAPTTDP1
SCHEMBL2268378 0.71 OPRM1 (0.38) GAAMAPTALOX12CRHBPHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed