SCHEMBL227244

SCHEMBL227244

CCCCc1ccc2c(c1)Sc1cc(CCCC)ccc1N2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 3/20 0.46
SKP2 Q13309 1/20 0.44
NOX1 Q9Y5S8 5/20 0.40
MAPK1 P28482 3/20 0.40
GAA P10253 3/20 0.40
MAPT P10636 3/20 0.40
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
HTT P42858 2/20 0.40
HPGD P15428 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CA2 P00918 2/20 0.39
CA1 P00915 1/20 0.39
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29640461 1.00 SNCA (0.46) SNCASKP2NOX1MAPK1GAA
SCHEMBL8142919 0.93 PTGS2 (0.46) SNCALMNAALDH1A1HSD17B10CYP3A4
SCHEMBL7765522 0.93 PTGS2 (0.46) SNCALMNAALDH1A1HSD17B10CYP3A4
SCHEMBL29640428 0.93 PTGS2 (0.46) SNCALMNAALDH1A1HSD17B10CYP3A4
SCHEMBL225844 0.93 PTGS2 (0.46) SNCALMNAALDH1A1HSD17B10CYP3A4
SCHEMBL29399785 0.93 PTGS2 (0.46) SNCALMNAALDH1A1HSD17B10CYP3A4
SCHEMBL8147738 0.92 NOX1 (0.53) SNCANOX1MAPK1GAAMAPT
SCHEMBL8150371 0.86 NOX1 (0.50) SNCANOX1MAPK1GAAMAPT
SCHEMBL223661 0.86 NOX1 (0.50) SNCANOX1MAPK1GAAMAPT
SCHEMBL8156091 0.86 NOX1 (0.50) SNCANOX1MAPK1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6210536-B1 DISTILLATION OF ACRYLIC OR METHACRYLIC ACID OR ESTER IN PRESENCE OF POLYMERIZATION INHIBITOR COMPRISING N,N*-DINITROSO PHENYLENEDIAMINE COMPOUND, A HYDROQUINONE OR HYDROQUINONE MONOMETHYL ETHER, PHENYLENEDIAMINE COMPOUND, PHENOTHIAZINE UNIROYAL CHEMICAL COMPANY, INC. 2001-04-03 US claimed
EP-0522709-B1 Polymerization inhibitors for acrylic acids and esters UNIROYAL CHEM CO INC (US) 1996-08-21 EP claimed
EP-0522709-A2 Polymerization inhibitors for acrylic acids and esters UNIROYAL CHEMICAL COMPANY, Inc. (US) 1993-01-13 EP claimed
EP-0334500-B1 VINYL AROMATIC COMPOSITONS STABILIZED AGAINST POLYMERIZATION UNIROYAL CHEMICAL COMPANY, Inc. (US) 1991-06-26 EP claimed
US-4915873-A PHENOTHIAZINE AND ARYL-SUBSTITUTED PHENYLENEDIAMINE UNIROYAL CHEMICAL COMPANY, INC. (US) 1990-04-10 US claimed
EP-0334500-A1 Vinyl aromatic compositons stabilized against polymerization UNIROYAL CHEMICAL COMPANY, Inc. (US) 1989-09-27 EP claimed
EP-0325059-A2 Polymerization inhibitor composition for vinyl aromatic compounds UNIROYAL CHEMICAL COMPANY, Inc. (US) 1989-07-26 EP claimed
US-4363745-A STERICALLY HINDERED PHENOL, BIS(A,A-DIMETHYLBENZYL) DIPHENYLAMINE AND A PHENOTHIAZINE COMPOUND STABILIZERS THE DOW CHEMICAL COMPANY (US) 1982-12-14 US claimed
US-4275173-A SYNERGISTIC COMBINATION OF A STERICALLY HINDERED PHENOL AND 4,4*-BIS/A,A-DIMETHYLBENZYL/DIPHENYL AMINE AND A PHENOTHIAZINE PROVIDE OXIDATION RESISTANCE THE DOW CHEMICAL COMPANY (US) 1981-06-23 US claimed
US-4265783-A SYNERGISTIC COMBINATION OF STERIC HINDERED PHENOL, 4,4*-BIS/A,A-DIMETHYL BENZYL/DIPHENYLAMINE AND A PHENOTHIAZINE THE DOW CHEMICAL COMPANY (US) 1981-05-05 US claimed
US-4010211-A 2,6-DI-TERT-BUTYL-P-CRESOL, DISUBSTITUTED DIPHENYLAMINE, PHENOTHIAZINE COMPOUND OLIN CORPORATION (US) 1977-03-01 US claimed
US-20260103652-A1 MACROMOLECULAR CORROSION (McIn) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORP (US) 2026-04-16 US disclosed
US-12492352-B2 Macromolecular corrosion (MCIN) inhibitors: structures, methods of making and using the same POLNOX CORPORATION (US) 2025-12-09 US disclosed
US-12180312-B2 Composition for the immediate termination of a free-radical polymerization and uses thereof SPECIALTY OPERATIONS FRANCE (FR) 2024-12-31 US disclosed
WO-2024214816-A1 PHOTOSENSITIVE RESIN LAMINATE AND METHOD FOR FORMING RESIST PATTERN 旭化成株式会社 2024-10-17 WO disclosed
EP-0325059-A2 Polymerization inhibitor composition for vinyl aromatic compounds UNIROYAL CHEMICAL COMPANY, Inc. (US) 1989-07-26 EP disclosed
US-4363745-A STERICALLY HINDERED PHENOL, BIS(A,A-DIMETHYLBENZYL) DIPHENYLAMINE AND A PHENOTHIAZINE COMPOUND STABILIZERS THE DOW CHEMICAL COMPANY (US) 1982-12-14 US disclosed
US-4275173-A SYNERGISTIC COMBINATION OF A STERICALLY HINDERED PHENOL AND 4,4*-BIS/A,A-DIMETHYLBENZYL/DIPHENYL AMINE AND A PHENOTHIAZINE PROVIDE OXIDATION RESISTANCE THE DOW CHEMICAL COMPANY (US) 1981-06-23 US disclosed
US-4265783-A SYNERGISTIC COMBINATION OF STERIC HINDERED PHENOL, 4,4*-BIS/A,A-DIMETHYL BENZYL/DIPHENYLAMINE AND A PHENOTHIAZINE THE DOW CHEMICAL COMPANY (US) 1981-05-05 US disclosed
US-4010211-A 2,6-DI-TERT-BUTYL-P-CRESOL, DISUBSTITUTED DIPHENYLAMINE, PHENOTHIAZINE COMPOUND OLIN CORPORATION (US) 1977-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12180312-B2 Composition for the immediate termination of a free-radical polymerization and uses thereof NOX4, GPX4, TXN SNCA 2370/4885SKP2 1530/4885NOX1 18/4885
US-12492352-B2 Macromolecular corrosion (MCIN) inhibitors: structures, methods of making and using the same MB, NCLN, CPN1 SNCA 3897/4885SKP2 2414/4885NOX1 606/4885
US-20260103652-A1 MACROMOLECULAR CORROSION (McIn) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME MPO, CYC1, CBR1 SNCA 3493/4885SKP2 2296/4885NOX1 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.