Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22728365 | 0.83 | SLC6A4 (0.37) | SLC6A4SLC6A2IDO1HTR2AKCNH2 | |
| SCHEMBL22728309 | 0.77 | KDM4C (0.35) | — | |
| SCHEMBL257088 | 0.72 | PYCR1 (0.50) | PYCR1SLC6A4SLC6A2IDO1HTR2A | |
| SCHEMBL22728398 | 0.71 | PNMT (0.43) | PYCR1IDO1 | |
| SCHEMBL1569635 | 0.71 | CYP2A6 (0.49) | PYCR1SLC6A4SLC6A2IDO1 | |
| SCHEMBL811131 | 0.69 | PYCR1 (0.47) | PYCR1SLC6A4SLC6A2IDO1KCNH2 | |
| SCHEMBL22728334 | 0.68 | RIPK1 (0.41) | SLC6A4SLC6A2IDO1HTR2A | |
| SCHEMBL980220 | 0.67 | SLC6A4 (0.53) | PYCR1SLC6A4SLC6A2HTR2AKCNH2 | |
| SCHEMBL16992938 | 0.67 | PYCR1 (0.40) | PYCR1IDO1GGPS1GAA | |
| SCHEMBL22728367 | 0.67 | TAAR1 (0.33) | SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243027-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SAGE THERAPEUTICS, INC. (US) | 2020-12-03 | — | — | WO | disclosed |