SCHEMBL2274516

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4221601	0.87	ABCB1 (0.52)	ABCB1MAPTLMNA
	SCHEMBL12117498	0.86	ABCB1 (0.42)	ABCB1CYP1A2ERN1
	SCHEMBL1316259	0.86	LMNA (0.51)	RAB9AMAPTNPC1L3MBTL1LMNA
	SCHEMBL27696821	0.85	ABCB1 (0.38)	ABCB1RAB9AMAPTNPC1L3MBTL1
	SCHEMBL27696823	0.83	ABCB1 (0.38)	ABCB1RAB9AMAPTNPC1L3MBTL1
	SCHEMBL4210431	0.82	ALOX5 (0.43)	ABCB1MAPTNPC1CYP1A2CYP2C19
	SCHEMBL1315554	0.81	CYP17A1 (0.50)	ABCB1MAPT
	SCHEMBL1319017	0.81	BRD4 (0.47)	ABCB1MAPTLMNAERN1
	SCHEMBL12394318	0.80	DCLRE1B (0.56)	ABCB1RAB9AMAPTNPC1DCLRE1B
	SCHEMBL12466331	0.80	L3MBTL1 (0.42)	ABCB1RAB9AMAPTNPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.