SCHEMBL2275558

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2271446	0.89	PYGM (0.50)	SERPINE1HPSEPYGLPYGMMEN1
	SCHEMBL2271588	0.86	SERPINE1 (0.64)	SERPINE1HPSENR1H4TDP1GALK1
	SCHEMBL2274764	0.86	ALDH1A1 (0.47)	SERPINE1HPSETDP1GALK1CASP6
	SCHEMBL2270621	0.84	GALK1 (0.68)	SERPINE1HPSENR1H4TDP1GALK1
	SCHEMBL2276745	0.84	SERPINE1 (0.65)	SERPINE1HPSENR1H4TDP1GALK1
	SCHEMBL2270356	0.84	SERPINE1 (0.48)	SERPINE1HPSENR1H4TDP1GALK1
	SCHEMBL2272043	0.83	SERPINE1 (0.75)	SERPINE1HPSENR1H4TDP1GALK1
	SCHEMBL2273634	0.83	SERPINE1 (0.60)	SERPINE1HPSENR1H4TDP1GALK1
	SCHEMBL2271007	0.83	MEN1 (0.69)	SERPINE1HPSENR1H4PYGMMEN1
	SCHEMBL2275467	0.83	CYP2C9 (0.63)	SERPINE1HPSENR1H4TDP1GALK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.