SCHEMBL2284084

SCHEMBL2284084

CCCCCC1C(=O)N(Cl)C(CCCCC)N1Cl

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.31
ABHD16A O95870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4136352 0.73 TP53 (0.32) CYP1A2ABHD16A
SCHEMBL11859129 0.71 CYP1A2 (0.34) CYP1A2ABHD16A
SCHEMBL7887401 0.69 PTGS1 (0.42) CYP1A2
SCHEMBL8607884 0.68 CYP1A2 (0.31) CYP1A2
SCHEMBL11855850 0.67 ELANE (0.34) CYP1A2
SCHEMBL2278997 0.67 PTPN1 (0.35) CYP1A2
SCHEMBL8029695 0.67 MMP1 (0.38)
SCHEMBL4129548 0.65 PTPN1 (0.32) CYP1A2
SCHEMBL818514 0.63
SCHEMBL8032985 0.63 ALDH1A1 (0.33) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100272783-A1 Methods of Treating Infections of the Nail NOVABAY PHARMACEUTICALS, INC. 2010-10-28 US claimed
WO-2010124237-A1 METHODS OF TREATING INFECTIONS OF THE NAIL NOVABAY PHARMACEUTICALS INC. (US) 2010-10-28 WO claimed
US-20090239907-A1 METHODS AND COMPOSITIONS FOR TREATING FISH DISEASES HALOSOURCE, INC. (US) 2009-09-24 US claimed
EP-1996187-A2 METHODS AND COMPOSITIONS FOR TREATING FISH DISEASES Halosource, Inc. (US) 2008-12-03 EP claimed
WO-2008115225-A2 METHODS AND COMPOSITIONS FOR TREATING FISH DISEASES HALOSOURCE, INC. (US) 2008-09-25 WO claimed
EP-0513239-B1 N,N'-DIHALOIMIDAZOLIDIN-4-ONES UNIV AUBURN (US) 1998-04-08 EP claimed
US-8563587-B2 Methods and compositions for treating fish diseases HALOSOURCE, INC. (US) 2013-10-22 US disclosed
EP-2531026-A1 POLYSACCHARIDE BASED ANTIMICROBIAL FORMULATIONS NovaBay Pharmaceuticals, Inc. (US) 2012-12-12 EP disclosed
WO-2011097324-A1 POLYSACCHARIDE BASED ANTIMICROBIAL FORMULATIONS NOVABAY PHARMACEUTICALS, INC. (US) 2011-08-11 WO disclosed
US-20110190392-A1 Polysaccharide Based Antimicrobial Formulations NOVABAY PHARMACEUTICALS, INC. 2011-08-04 US disclosed
WO-2010124237-A1 METHODS OF TREATING INFECTIONS OF THE NAIL NOVABAY PHARMACEUTICALS INC. (US) 2010-10-28 WO disclosed
US-20100272783-A1 Methods of Treating Infections of the Nail NOVABAY PHARMACEUTICALS, INC. 2010-10-28 US disclosed
US-20090239907-A1 METHODS AND COMPOSITIONS FOR TREATING FISH DISEASES HALOSOURCE, INC. (US) 2009-09-24 US disclosed
WO-2008115225-A2 METHODS AND COMPOSITIONS FOR TREATING FISH DISEASES HALOSOURCE, INC. (US) 2008-09-25 WO disclosed
EP-0513239-B1 N,N'-DIHALOIMIDAZOLIDIN-4-ONES UNIV AUBURN (US) 1998-04-08 EP disclosed
EP-0513239-A4 N,N'-DIHALOIMIDAZOLIDIN-4-ONES 1993-03-10 EP disclosed
EP-0513239-A1 N,N'-DIHALOIMIDAZOLIDIN-4-ONES AUBURN UNIVERSITY (US) 1992-11-19 EP disclosed
US-5126057-A Stabilizers against solar radiation AUBURN RESEARCH FOUNDATION (US) 1992-06-30 US disclosed
US-5057612-A Stable, noncorrosive bicoide, disinfectant AUBURN RESEARCH FOUNDATION (US) 1991-10-15 US disclosed
WO-1991010623-A1 N,N'-DIHALOIMIDAZOLIDIN-4-ONES AUBURN UNIVERSITY (US) 1991-07-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100272783-A1 Methods of Treating Infections of the Nail POLR1C, TYR, NACA CYP1A2 689/4885ABHD16A 3679/4885
US-20090239907-A1 METHODS AND COMPOSITIONS FOR TREATING FISH DISEASES AQP3, AQP1, NISCH CYP1A2 1522/4885ABHD16A 746/4885
US-20110190392-A1 Polysaccharide Based Antimicrobial Formulations FUT6, FUT5, OGT CYP1A2 2672/4885ABHD16A 1488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.