Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793551 | 1.00 | CYP3A4 (0.52) | CYP3A4TSHRGAAKMT2ACYP2C9 | |
| Hydrochloric Acid SCHEMBL9788683 | 0.98 | GAA (0.53) | CYP3A4TSHRGAAKMT2ACYP2C9 | |
| Hydrochloric Acid SCHEMBL9788679 | 0.98 | GAA (0.53) | CYP3A4TSHRGAAKMT2ACYP2C9 | |
| SCHEMBL2258320 | 0.82 | CYP3A4 (0.52) | CYP3A4TSHRGAAKMT2ACYP2C9 | |
| SCHEMBL11811790 | 0.78 | CYP3A4 (0.46) | CYP3A4TSHRGAAKMT2AALDH1A1 | |
| SCHEMBL5950905 | 0.77 | CYP3A4 (0.47) | CYP3A4TSHRGAAKMT2ACYP2C9 | |
| SCHEMBL6814753 | 0.77 | CYP3A4 (0.42) | CYP3A4TSHRGAAKMT2ACYP2C9 | |
| SCHEMBL736511 | 0.77 | FSCN1 (0.69) | CYP3A4TSHRGAAKMT2ACYP2C9 | |
| SCHEMBL6811930 | 0.77 | CYP3A4 (0.51) | CYP3A4TSHRGAAKMT2ACYP2C9 | |
| SCHEMBL10956325 | 0.76 | ALDH1A1 (0.44) | CYP3A4TSHRGAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250017909-A1 | METHODS FOR THE TREATMENT OF CONDITIONS RELATED TO HYDROGEN SULFIDE | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2025-01-16 | — | — | US | disclosed |
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | SAINT LOUIS UNIVERSITY (US) | 2024-04-11 | — | — | US | disclosed |
| US-11925623-B2 | Methods for the treatment of conditions related to hydrogen sulfide | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-03-12 | — | — | US | disclosed |
| US-11400084-B2 | Aminoamide compounds | BIOTHERYX, INC. (US) | 2022-08-02 | — | — | US | disclosed |
| US-20220023267-A1 | METHODS FOR THE TREATMENT OF CONDITIONS RELATED TO HYDROGEN SULFIDE | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-01-27 | — | — | US | disclosed |
| US-10183082-B2 | PET probes of radiofluorinated carboximidamides for IDO-targeted imaging | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2019-01-22 | — | — | US | disclosed |
| US-10183082-B2 | PET probes of radiofluorinated carboximidamides for IDO-targeted imaging | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2019-01-22 | — | — | US | disclosed |
| EP-3004118-B1 | USE OF CONDENSED BENZO[B]THIAZINE DERIVATIVES AS CYTOPROTECTANTS | ARANDA PHARMA LTD (FI) | 2018-12-19 | — | — | EP | disclosed |
| US-20170340758-A1 | PET PROBES OF RADIOFLUORINATED CARBOXIMIDAMIDES FOR IDO-TARGETED IMAGING | H LEE MOFFITT CANCER CT & RES (US) | 2017-11-30 | — | — | US | disclosed |
| US-20170340758-A1 | PET PROBES OF RADIOFLUORINATED CARBOXIMIDAMIDES FOR IDO-TARGETED IMAGING | H LEE MOFFITT CANCER CT & RES (US) | 2017-11-30 | — | — | US | disclosed |
| US-4908304-A | Silver halide emulsion contains hydroxytetrazaindene compound and electron beam hardenable resin | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1990-03-13 | — | — | US | disclosed |
| US-4642383-A | 2,21-DIHYDROXYDIPHENYL SULFIDES, SULFOXIDES, AND SULFONES | JAMES RIVER GRAPHICS, INC. (US) | 1987-02-10 | — | — | US | disclosed |
| EP-0192638-A1 | LEMON-YELLOW DIAZO COMPOSITIONS | JAMES RIVER-GRAPHICS, INC. (US) | 1986-09-03 | — | — | EP | disclosed |
| EP-0175366-A2 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1986-03-26 | — | — | EP | disclosed |
| WO-1986001505-A1 | LEMON-YELLOW DIAZO COMPOSITIONS | JAMES RIVER GRAPHICS, INC. (US) | 1986-03-13 | — | — | WO | disclosed |
| US-4248591-A | HAIR DYES | L'OREAL (FR) | 1981-02-03 | — | — | US | disclosed |
| US-4221729-A | HAIR DYES | L'OREAL (FR) | 1980-09-09 | — | — | US | disclosed |
| US-4163059-A | Pesticidally active 4,5-dichloro-3-substituted-phenylimino-1,2-dithiolenes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-31 | — | — | US | disclosed |
| US-3977825-A | Indoanilines in keratinic fiber dye cmpositions | L'OREAL (FR) | 1976-08-31 | — | — | US | disclosed |
| US-3931215-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11925623-B2 | Methods for the treatment of conditions related to hydrogen sulfide | CTH, HMBS, CBS | CYP3A4 2038/4885TSHR 3457/4885GAA 165/4885 |
| US-10183082-B2 | PET probes of radiofluorinated carboximidamides for IDO-targeted imaging | IDO1, IDO2, KMO | CYP3A4 2571/4885TSHR 3669/4885GAA 3509/4885 |
| US-20250017909-A1 | METHODS FOR THE TREATMENT OF CONDITIONS RELATED TO HYDROGEN SULFIDE | CTH, HMBS, CBS | CYP3A4 2038/4885TSHR 3457/4885GAA 165/4885 |
| US-20220023267-A1 | METHODS FOR THE TREATMENT OF CONDITIONS RELATED TO HYDROGEN SULFIDE | CTH, HMBS, CBS | CYP3A4 2038/4885TSHR 3457/4885GAA 165/4885 |
| US-20170340758-A1 | PET PROBES OF RADIOFLUORINATED CARBOXIMIDAMIDES FOR IDO-TARGETED IMAGING | IDO1, IDO2, IDH1 | CYP3A4 2779/4885TSHR 3450/4885GAA 3458/4885 |
| US-11400084-B2 | Aminoamide compounds | DNPEP, BCAT2, AADAT | CYP3A4 4515/4885TSHR 3973/4885GAA 421/4885 |
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | ABCC1, ARG1, SLC11A2 | CYP3A4 2607/4885TSHR 4447/4885GAA 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.