Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | HTT | P42858 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | RNF4 | P78317 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20528840 | 0.86 | ALDH1A1 (0.39) | ALDH1A1HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL22845018 | 0.80 | ALDH1A1 (0.40) | ALDH1A1HTTSMN1; SMN2HPGDLMNA | |
| SCHEMBL19911199 | 0.78 | NSD2 (0.40) | ALDH1A1SMN1; SMN2HPGDLMNAMEN1 | |
| SCHEMBL13404895 | 0.77 | MGLL (0.37) | ALDH1A1HTTSMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL22833186 | 0.76 | KDM4E (0.54) | ALDH1A1HTTSMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL10076741 | 0.74 | L3MBTL1 (0.45) | ALDH1A1SMN1; SMN2HPGDL3MBTL1LMNA | |
| SCHEMBL12092089 | 0.74 | L3MBTL1 (0.54) | ALDH1A1SMN1; SMN2L3MBTL1LMNAMEN1 | |
| SCHEMBL6018300 | 0.72 | HTR3E (0.41) | ALDH1A1HTTSMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL17747110 | 0.72 | CA12 (0.46) | ALDH1A1SMN1; SMN2HPGDL3MBTL1LMNA | |
| SCHEMBL7769437 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HPGDLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220249687-A1 | BIS(2-HALOACETAMIDO)-COMPOUNDS FOR USE AS LINKING AGENTS AND RESULTANT PRODUCTS WHICH COMPRISE ANTIBODIES, HALF-ANTIBODIES AND ANTIBODY FRAGMENTS | THE UNIVERSITY OF BATH (GB) | 2022-08-11 | — | — | US | disclosed |
| WO-2020260514-A1 | BIS(2-HALOACETAMIDO)-COMPOUNDS FOR USE AS LINKING AGENTS AND RESULTANT PRODUCTS WHICH COMPRISE ANTIBODIES, HALF-ANTIBODIES AND ANTIBODY FRAGMENTS | THE UNIVERSITY OF BATH (GB) | 2020-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220249687-A1 | BIS(2-HALOACETAMIDO)-COMPOUNDS FOR USE AS LINKING AGENTS AND RESULTANT PRODUCTS WHICH COMPRISE ANTIBODIES, HALF-ANTIBODIES AND ANTIBODY FRAGMENTS | PAICS, PA2G4, GSTM2 | ALDH1A1 307/4885HTT 568/4885SMN1; SMN2 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.