Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14174816 | 0.79 | APAF1 (0.53) | ALDH1A1KMT2AMAPTLMNACYP2C19 | |
| SCHEMBL28839873 | 0.75 | ALDH1A1 (0.63) | ALDH1A1KMT2AMAPTLMNACYP2C19 | |
| SCHEMBL2526727 | 0.73 | LMNA (0.57) | ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL5709612 | 0.72 | HSD17B10 (0.57) | KMT2ALMNAPOLBMEN1 | |
| SCHEMBL7445085 | 0.72 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTLMNACYP2C19 | |
| SCHEMBL16215077 | 0.72 | LMNA (0.53) | ALDH1A1KMT2ALMNAPOLBMEN1 | |
| SCHEMBL6500535 | 0.71 | ALDH1A1 (0.67) | ALDH1A1KMT2AMAPTLMNACYP2C19 | |
| SCHEMBL321369 | 0.71 | ALDH1A1 (1.00) | ALDH1A1KMT2AMAPTLMNACYP2C19 | |
| SCHEMBL2910116 | 0.70 | GLA (0.58) | ALDH1A1KMT2AMAPTLMNACYP2C19 | |
| Hydrochloric Acid SCHEMBL11682498 | 0.69 | LMNA (0.53) | ALDH1A1KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840514-B2 | Catalysts and methods for enantioselective conjugate addition of amines to unsaturated electrophiles | NORTHWESTERN UNIVERSITY (US) | 2023-12-12 | — | — | US | disclosed |
| US-20210002221-A1 | CATALYSTS AND METHODS FOR ENANTIOSELECIVE CONJUGATE ADDITION OF AMINES TO UNSATURATED ELECTROPHILES | NORTHWESTERN UNIVERSITY | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11840514-B2 | Catalysts and methods for enantioselective conjugate addition of amines to unsaturated electrophiles | AADAC, COASY, PAICS | ALDH1A1 142/4885KMT2A 1436/4885MAPT 3807/4885 |
| US-20210002221-A1 | CATALYSTS AND METHODS FOR ENANTIOSELECIVE CONJUGATE ADDITION OF AMINES TO UNSATURATED ELECTROPHILES | COASY, AADAC, AOC1 | ALDH1A1 97/4885KMT2A 1916/4885MAPT 3952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.