Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDCBP | O00560 | 5/20 | 0.44 |
| ▸ | SDC2 | P34741 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | VHL | P40337 | 1/20 | 0.37 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180906 | 0.89 | ALDH1A1 (0.43) | SDCBPSDC2LMNATHRBTP53 | |
| SCHEMBL2296052 | 0.87 | SDCBP (0.43) | SDCBPSDC2LMNATHRBTP53 | |
| SCHEMBL2179986 | 0.86 | PTPRC (0.46) | SDCBPSDC2LMNATHRBTP53 | |
| SCHEMBL2179993 | 0.86 | PTPRC (0.46) | SDCBPSDC2LMNATHRBTP53 | |
| SCHEMBL2282134 | 0.82 | THRB (0.52) | SDCBPSDC2LMNATHRBTP53 | |
| SCHEMBL2177345 | 0.82 | ITGA4 (0.43) | SDCBPSDC2LMNATHRBTP53 | |
| SCHEMBL2178996 | 0.82 | DGAT1 (0.45) | SDCBPSDC2LMNATHRBTP53 | |
| SCHEMBL2177537 | 0.82 | LMNA (0.40) | SDCBPSDC2LMNATHRBTP53 | |
| SCHEMBL2178545 | 0.82 | DGAT1 (0.45) | SDCBPSDC2LMNATHRBTP53 | |
| SCHEMBL2177533 | 0.82 | LMNA (0.40) | SDCBPSDC2LMNATHRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519500-A1 | INHIBITORS OF DIACYLGLYCEROL ACYL TRANSFERASE | Piramal Healthcare Ltd. (IN) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080718-A1 | INHIBITORS OF DIACYLGLYCEROL ACYL TRANSFERASE | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |