SCHEMBL22909609

SCHEMBL22909609

CCc1ccc(Cc2c(F)c(F)c(F)c(F)c2SN(C)C)c(CC)c1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22909469 0.72 ALDH1A1 (0.37)
SCHEMBL5050079 0.70 TRPA1 (0.44)
SCHEMBL22909600 0.69 IDO1 (0.36)
SCHEMBL22909496 0.68 LMNA (0.33)
SCHEMBL22909581 0.67 DAO (0.37)
SCHEMBL444673 0.66 TRPA1 (0.48)
SCHEMBL22909233 0.66 GFER (0.42) SIGMAR1
SCHEMBL22909374 0.65 TAAR1 (0.39) SIGMAR1
SCHEMBL22909449 0.63 HDAC3 (0.34)
SCHEMBL22909452 0.63 CYP2A6 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021009568-A1 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF 2692372 ONTARIO, INC. (CA) 2021-01-21 WO disclosed