SCHEMBL22972953

SCHEMBL22972953

O=P1(c2ccccc2)c2cc(O)ccc2Nc2ccc(N3CCOCC3)cc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 7/20 0.45
PRKDC P78527 4/20 0.43
PIK3CD O00329 2/20 0.43
PIK3CA P42336 2/20 0.43
PIK3CB P42338 2/20 0.43
PIK3CG P48736 2/20 0.43
MAPT P10636 4/20 0.40
PKM P14618 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ESR1 P03372 1/20 0.40
ALOX15 P16050 1/20 0.40
ESR2 Q92731 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KMO O15229 1/20 0.40
LMNA P02545 1/20 0.39
TSHR P16473 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22972944 0.93 KIF11 (0.46) KIF11PRKDCPIK3CDPIK3CAPIK3CB
SCHEMBL22972962 0.81 MAOA (0.33) MEN1KMT2AESR1ESR2NPC1
SCHEMBL22972960 0.69 KIF11 (0.47) KIF11PRKDCPIK3CDPIK3CAPIK3CB
SCHEMBL23767966 0.69 KIF11 (0.50) KIF11PRKDCPIK3CDPIK3CAPIK3CB
SCHEMBL2478090 0.66 PRKDC (0.58) KIF11PRKDCPIK3CDPIK3CAPIK3CB
SCHEMBL4649483 0.66 MAPT (0.59) KIF11PRKDCPIK3CDPIK3CAPIK3CB
SCHEMBL226009 0.65 KMO (0.60) KIF11PRKDCPIK3CDPIK3CAPIK3CB
SCHEMBL32211602 0.65 KMO (0.60) KIF11PRKDCPIK3CDPIK3CAPIK3CB
Phenol SCHEMBL28278427 0.65 LMNA (0.76) PRKDCPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL20696085 0.64 KMO (0.58) KIF11PRKDCPIK3CDPIK3CAPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3774821-B1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS ORTA DOGU TEKNIK UNIV (TR) 2025-04-30 EP disclosed
US-20240342286-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS ORTA DOGU TEKNIK UNIVERSITESI (TR) 2024-10-17 US disclosed
EP-4001285-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS ORTA DOGU TEKNIK UNIVERSITESI (TR) 2022-05-25 EP disclosed
US-20210252152-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS ORTA DOGU TEKNIK UNIVERSITESI (TR) 2021-08-19 US disclosed
US-20210252152-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS ORTA DOGU TEKNIK UNIVERSITESI (TR) 2021-08-19 US disclosed
EP-3774821-A2 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS ORTA DOGU TEKNIK UNIVERSITESI (TR) 2021-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210252152-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS PPIF, MT-ND2, PPOX KIF11 2184/4885PRKDC 1574/4885PIK3CD 4235/4885
US-20240342286-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS PPIF, MT-ND2, PPOX KIF11 2184/4885PRKDC 1574/4885PIK3CD 4235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.