Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | THPO | P40225 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999598 | 0.87 | KDM4E (0.63) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL5599294 | 0.87 | KDM4E (0.63) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL112332 | 0.87 | SMN1; SMN2 (0.63) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL112331 | 0.87 | SMN1; SMN2 (0.63) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL7999610 | 0.87 | KDM4E (0.63) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL14088106 | 0.87 | SMN1; SMN2 (0.63) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL23870628 | 0.85 | KDM4E (0.61) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL7758252 | 0.85 | KDM4E (0.61) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL6815850 | 0.85 | KDM4E (0.61) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL16011717 | 0.83 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150209434-A1 | MUCOADHESIVE POLYMERS HAVING VITAMIN B PARTIAL STRUCTURES | THIOMATRIX FORSCHUNGS UND BERATUNGS GMBH (AT) | 2015-07-30 | — | — | US | claimed |
| US-20140235717-A1 | FOOD PRODUCTS, PREPARATION, AND THERAPEUTIC METHODS | SCHLOSS JOHN V (US) | 2014-08-21 | — | — | US | claimed |
| US-20120322868-A1 | FOOD PRODUCTS, PREPARATION, AND THERAPEUTIC METHODS | SCHLOSS JOHN V (US) | 2012-12-20 | — | — | US | claimed |
| WO-2011103577-A1 | IMPROVED FOOD PRODUCTS, PREPARATION, AND THERAPEUTIC METHODS | SCHLOSS JOHN V (US) | 2011-08-25 | — | — | WO | claimed |
| CN-110088118-B | Crystal of glutathione trisulfide dihydrate and method for producing same | 协和发酵生化株式会社 | 2023-04-04 | — | — | CN | disclosed |
| US-11186610-B2 | Crystal of glutathione trisulfide dihydrate and method for producing same | KYOWA HAKKO BIO CO., LTD. (JP) | 2021-11-30 | — | — | US | disclosed |
| US-20200079818-A1 | CRYSTAL OF GLUTATHIONE TRISULFIDE DIHYDRATE AND METHOD FOR PRODUCING SAME | KYOWA HAKKO BIO CO., LTD. (JP) | 2020-03-12 | — | — | US | disclosed |
| EP-3560947-A1 | CRYSTALS OF GLUTATHIONE TRISULFIDE DIHYDRATE AND METHOD OF PRODUCING SAME | Kyowa Hakko Bio Co., Ltd. (JP) | 2019-10-30 | — | — | EP | disclosed |
| EP-3429573-A1 | COMPOSITIONS FOR CONTROLLED RELEASE OF CYSTEAMINE AND SYSTEMIC TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS | Thiogenesis Therapeutics, Inc. (US) | 2019-01-23 | — | — | EP | disclosed |
| WO-2017161318-A1 | COMPOSITIONS FOR CONTROLLED RELEASE OF CYSTEAMINE AND SYSTEMIC TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS | THIOGENESIS THERAPEUTICS, INC. (US) | 2017-09-21 | — | — | WO | disclosed |
| US-8975283-B2 | Pharmacologically active compounds containing sulfur | JON PTY LIMITED (AU) | 2015-03-10 | — | — | US | disclosed |
| EP-2664614-A1 | PALLADIUM-COPPER CATALYSTS FOR THE HOMOGENEOUS SELECTIVE OXIDATION OF THIOL GROUPS | "Ivy Pharm" Limited Liability Company (RU) | 2013-11-20 | — | — | EP | disclosed |
| US-20130289108-A1 | Palladium-Copper Catalysts for the Homogeneous Selective Oxidation of Thiol Groups | "IVY PHARM" LIMITED LIABILITY COMPANY (RU) | 2013-10-31 | — | — | US | disclosed |
| US-20130123504-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS CONTAINING SULFUR | JON PTY LIMITED (AU) | 2013-05-16 | — | — | US | disclosed |
| US-8362041-B2 | Pharmacologically active compounds containing sulfur | JON PTY LIMITED (AU) | 2013-01-29 | — | — | US | disclosed |
| US-20090042947-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS CONTAINING SULFUR | JON PTY LIMITED (AU) | 2009-02-12 | — | — | US | disclosed |
| WO-2007056817-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS CONTAINING SULFUR | JON PTY LIMITED (AU) | 2007-05-24 | — | — | WO | disclosed |
| US-5346599-A | Monitoring extent of disease associated with abnormal levels of nitric oxide, nitrosonium or nitroxyl | BRIGHAM AND WOMEN'S HOSPITAL | 1994-09-13 | — | — | US | disclosed |
| WO-1994017398-A1 | CAPILLARY ZONE ELECTROPHORESIS OF THIOLS AND THEIR DERIVATIVES | BRIGHAM AND WOMEN'S HOSPITAL (US) | 1994-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123504-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS CONTAINING SULFUR | SCLY, STS, SQOR | KDM4E 4559/4885MAPT 4757/4885THRB 1853/4885 |
| US-20130289108-A1 | Palladium-Copper Catalysts for the Homogeneous Selective Oxidation of Thiol Groups | SOD1, SOD3, GSTM2 | KDM4E 4042/4885MAPT 3337/4885THRB 2817/4885 |
| US-20120322868-A1 | FOOD PRODUCTS, PREPARATION, AND THERAPEUTIC METHODS | SLC7A11, CTH, GNMT | KDM4E 2841/4885MAPT 1234/4885THRB 98/4885 |
| US-20090042947-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS CONTAINING SULFUR | SCLY, STS, SQOR | KDM4E 4696/4885MAPT 4684/4885THRB 1730/4885 |
| US-20140235717-A1 | FOOD PRODUCTS, PREPARATION, AND THERAPEUTIC METHODS | SLC7A11, CTH, GNMT | KDM4E 2841/4885MAPT 1234/4885THRB 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.