SCHEMBL2298799

SCHEMBL2298799

Cc1cc(-c2c(S(C)(=O)=O)ccc(C(=O)c3cnn(C)c3O)c2C)on1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.30
CSF1R P07333 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2215157 0.90 CSF1R (0.33) KDM4EUSP2ALDH1A1TSHRKMT2A
SCHEMBL7988667 0.84 KDM4E (0.31) KDM4EUSP2ALDH1A1TSHR
SCHEMBL28927865 0.80 P2RX3 (0.33)
SCHEMBL27619387 0.80 KDM4E (0.32) KDM4EUSP2ALDH1A1TSHRKMT2A
SCHEMBL12602531 0.80 SMN1; SMN2 (0.32) ALDH1A1NPC1RAB9ALMNATP53
SCHEMBL6587430 0.79 ALDH1A1 (0.50) KDM4EUSP2ALDH1A1TSHRKMT2A
SCHEMBL5204516 0.78 ALDH1A1 (0.35) KDM4EUSP2ALDH1A1TSHRKMT2A
SCHEMBL6587396 0.78 KDM4E (0.40) KDM4EUSP2ALDH1A1TSHRKMT2A
SCHEMBL8310173 0.78 RAB9A (0.36) KDM4EUSP2ALDH1A1TSHRKMT2A
Topramezone SCHEMBL29566850 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7375058-B2 Herbicidal mixtures based on 3-phenyluracils BASF AKTIENGESELLSCHAFT (DE) 2008-05-20 US claimed
US-20070093390-A1 Synergistically acting herbicidal mixtures BASF AKTIENGESELLSCHAFT (DE) 2007-04-26 US claimed
US-20070060478-A1 Herbicidal mixtures comprising a safener BASF AKTIENGESELLSCHAFT (DE) 2007-03-15 US claimed
EP-1429609-B1 HERBICIDAL MIXTURES BASED ON 3-PHENYLURACILS BASF AG (DE) 2007-03-07 EP claimed
EP-1605759-B1 HERBICIDAL MIXTURES COMPRISING A SAFENER BASF AG (DE) 2006-08-23 EP claimed
CN-1761394-A Synergistically acting herbicidal mixtures BASF AG (DE) 2006-04-19 CN claimed
CN-1761393-A Herbicidal mixtures comprising a safener BASF AG (DE) 2006-04-19 CN claimed
EP-1458237-B1 HERBICIDAL MIXTURE BASED ON 7-PYRAZOLYLBENZOXAZOLES BASF AG (DE) 2006-04-12 EP claimed
US-20050037923-A1 Herbicidal mixture based on 7-pyrazolybenzoxazoles BASF AKTIENGESELLSCHAFT (DE) 2005-02-17 US claimed
US-20040235665-A1 used in combination with other herbicides and possibly plant safening agents in order to reduce toxic effect on plants BASF AKTIENGESELLSCHAFT (DE) 2004-11-25 US claimed
US-8003569-B2 Herbicidal mixtures comprising a safener BASF SE (DE) 2011-08-23 US disclosed
US-8003569-B2 Herbicidal mixtures comprising a safener BASF SE (DE) 2011-08-23 US disclosed
US-7632782-B2 4-(2-Methyl-3-(4,5-dihydroisoxazol-3-yl)-4-methylsulfonyl-benzoyl)-1-methyl-5-hydroxy-1H-pyrazole and a sulfonylurea herbicide of the formula 1-(((2-dimethylamido-),4-(carbonylamino-)phenyl)-sulfonyl-),3-((4,6-dimethoxy-)pyrimidin-2-yl)urea; cropprotection; increased activity and/or selectivity BASF AKTIENGESELLSCHAFT (DE) 2009-12-15 US disclosed
US-7521395-B2 Synergistically acting herbicidal mixtures BASF AKTIENGESELLSCHAFT (DE) 2009-04-21 US disclosed
US-20090023588-A1 HERBICIDAL MIXTURES COMPRISING A SAFENER BASF SE (DE) 2009-01-22 US disclosed
WO-2004010779-A2 SYNERGISTICALLY ACTING HERBICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2004-02-05 WO disclosed
WO-2004008849-A2 SYNERGISTICALLY ACTING HERBICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2004-01-29 WO disclosed
WO-2004008861-A1 SYNERGISTICALLY ACTING HERBICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2004-01-29 WO disclosed
US-6683027-B2 SYNERGISTICALLY EFFECTIVE AMOUNT OF SUBSTITUTED 2-PHENYL PYRIMIDINE COMPOUNDS WITH OTHER HERBICIDAL COMPOUND, WHICH IS ACTIVE AGAINST BROAD-LEAVED WEEDS AND/OR ANNUAL GRASSES BASF AKTIENEGESELLSCHAFT (DE) 2004-01-27 US disclosed
US-20020055435-A1 Herbicidal mixtures INTELLECTUAL PROPERTY DEPARTMENT (DE) 2002-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070093390-A1 Synergistically acting herbicidal mixtures HPD, DDT, CYP4X1 KDM4E 902/4885USP2 1256/4885ALDH1A1 931/4885
US-20020055435-A1 Herbicidal mixtures DDT, CYP2W1, CYP1B1 KDM4E 2256/4885USP2 1898/4885ALDH1A1 30/4885
US-20050037923-A1 Herbicidal mixture based on 7-pyrazolybenzoxazoles DDT, CYP2W1, CYP3A7 KDM4E 3461/4885USP2 3770/4885ALDH1A1 291/4885
US-20040235665-A1 used in combination with other herbicides and possibly plant safening agents in order to reduce toxic effect on plants CYP2D6, COXFA4, ME3 KDM4E 1814/4885USP2 2821/4885ALDH1A1 720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.