Sugi Predict

Sugi Predict / Compounds / SCHEMBL2301397

SCHEMBL2301397

SCHEMBL2301397

[O]c1ccc(C=Cc2ccccc2)c(C=Cc2ccccc2)c1C=Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ NFE2L2 Q16236 4/20 0.44
▸ TRPA1 O75762 3/20 0.44
▸ CHAT P28329 3/20 0.40
▸ DPYD Q12882 1/20 0.40
▸ MAOB P27338 2/20 0.39
▸ CYP19A1 P11511 1/20 0.39
▸ MAOA P21397 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ ALOX5 P09917 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ CYP1A1 P04798 1/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP1B1 Q16678 1/20 0.39
▸ NR1H2 P55055 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3690347 1.00 NFE2L2 (0.44) NFE2L2TRPA1CHATDPYDMAOB
SCHEMBL2033487 0.87 NFE2L2 (0.54) NFE2L2TRPA1CHATMAOBCYP19A1
SCHEMBL2033485 0.87 NFE2L2 (0.54) NFE2L2TRPA1CHATMAOBCYP19A1
SCHEMBL3363528 0.78 NFE2L2 (0.45) NFE2L2TRPA1CHATMAOBCYP19A1
SCHEMBL478037 0.76 NFE2L2 (0.58) NFE2L2TRPA1CHATMAOBCYP19A1
SCHEMBL478036 0.76 NFE2L2 (0.58) NFE2L2TRPA1CHATMAOBCYP19A1
SCHEMBL41525 0.76 TRPA1 (0.59) NFE2L2TRPA1CHATMAOBALOX5
SCHEMBL41526 0.76 TRPA1 (0.59) NFE2L2TRPA1CHATMAOBALOX5
SCHEMBL29360472 0.76 TRPA1 (0.59) NFE2L2TRPA1CHATMAOBALOX5
Formaldehyde SCHEMBL28642478 0.76 TRPA1 (0.53) NFE2L2TRPA1CHATALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109354672-B Alkylene oxide urethane associative thickeners modified with hydrophobic oligomers 罗门哈斯公司 2021-10-15 — — CN claimed
US-12005038-B2 Methods suitable for disrupting a biofilm, and/or killing bacteria contained in a biofilm JOHNSON & JOHNSON CONSUMER INC. (US) 2024-06-11 — — US disclosed
US-11986447-B2 Methods suitable for the treatment of acne JOHNSON & JOHNSON CONSUMER INC. (US) 2024-05-21 — — US disclosed
US-20240139150-A1 METHODS AND COMPOSITIONS SUITABLE FOR THE TREATMENT OF ACNE KENVUE BRANDS LLC 2024-05-02 — — US disclosed
US-20240041043-A1 STORAGE STABLE AQUEOUS SUSPENSION CONCENTRATES Bayer Vapi Private Limited (IN) 2024-02-08 — — US disclosed
US-11890263-B2 Methods and compositions suitable for the treatment of acne JOHNSON & JOHNSON CONSUMER INC. (US) 2024-02-06 — — US disclosed
CN-116828985-A Storage-stable aqueous suspension concentrates 拜耳公司 2023-09-29 — — CN disclosed
EP-4196083-A1 METHODS AND COMPOSITIONS SUITABLE FOR THE TREATMENT OF ACNE Johnson & Johnson Consumer Inc. (US) 2023-06-21 — — EP disclosed
WO-2022128955-A1 STORAGE STABLE AQUEOUS SUSPENSION CONCENTRATES BAYER AKTIENGESELLSCHAFT (DE) 2022-06-23 — — WO disclosed
EP-4011209-A1 STORAGE STABLE AQUEOUS SUSPENSION CONCENTRATES Bayer Aktiengesellschaft (DE) 2022-06-15 — — EP disclosed
US-20110223125-A1 COMPOSITIONS WITH FREEZE THAW STABILITY RHODIA OPERATIONS (FR) 2011-09-15 — — US disclosed
WO-2011100660-A1 COMPOSITIONS WITH FREEZE THAW STABILITY RHODIA OPERATIONS (FR) 2011-08-18 — — WO disclosed
WO-2011100665-A2 RHEOLOGY MODIFIER COMPOSITIONS AND METHODS OF USE RHODIA OPERATIONS (FR) 2011-08-18 — — WO disclosed
WO-2011100071-A1 RHEOLOGY MODIFIER POLYMER RHODIA OPERATIONS (FR) 2011-08-18 — — WO disclosed
EP-2195389-A1 A METHOD TO IMPROVE THE COLOR ACCEPTANCE OF VISCOSITY STABILIZED LATEX PAINTS Elementis Specialties, Inc. (US) 2010-06-16 — — EP disclosed
WO-2009046131-A1 A METHOD TO IMPROVE THE COLOR ACCEPTANCE OF VISCOSITY STABILIZED LATEX PAINTS ELEMENTIS SPECIALTIES, INC. (US) 2009-04-09 — — WO disclosed
US-20090088516-A1 METHOD TO IMPROVE THE COLOR ACCEPTANCE OF VISCOSITY STABILIZED LATEX PAINTS ELEMENTIS SPECIALTIES, INC. 2009-04-02 — — US disclosed
EP-1345492-B1 HERBICIDE AGENT BAYER CROPSCIENCE GMBH (DE) 2006-02-08 — — EP disclosed
US-6693063-B2 HALOGENATED HYDROXYBENZONITRILE DERIVATIVE WITH SPECIFIC SURFACTANTS AVENTIS CROPSCIENCE GMBH (DE) 2004-02-17 — — US disclosed
US-20020115569-A1 Herbicidal composition AVENTIS CROPSCIENCE GMBH (DE) 2002-08-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11890263-B2 Methods and compositions suitable for the treatment of acne LGALS7; LGALS7B, MGAT3, ALG1 NFE2L2 4876/4885TRPA1 3730/4885CHAT 2116/4885
US-11986447-B2 Methods suitable for the treatment of acne CUTA, HSD17B12, HAO2 NFE2L2 1912/4885TRPA1 3998/4885CHAT 1695/4885
US-20110223125-A1 COMPOSITIONS WITH FREEZE THAW STABILITY C9, PUF60, BCL2L10 NFE2L2 3069/4885TRPA1 1488/4885CHAT 4791/4885
US-12005038-B2 Methods suitable for disrupting a biofilm, and/or killing bacteria contained in a biofilm HAO2, CUTA, HACL2 NFE2L2 3155/4885TRPA1 4468/4885CHAT 3372/4885
US-20240041043-A1 STORAGE STABLE AQUEOUS SUSPENSION CONCENTRATES SORD, SDHA, MDH1 NFE2L2 2653/4885TRPA1 4301/4885CHAT 3326/4885
US-20240139150-A1 METHODS AND COMPOSITIONS SUITABLE FOR THE TREATMENT OF ACNE LGALS7; LGALS7B, MGAT3, ALG1 NFE2L2 4876/4885TRPA1 3730/4885CHAT 2116/4885
US-20020115569-A1 Herbicidal composition CBR1, DDT, CYP1A1 NFE2L2 1312/4885TRPA1 687/4885CHAT 1086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.