Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 3/20 | 0.33 |
| ▸ | NPY1R | P25929 | 2/20 | 0.33 |
| ▸ | FURIN | P09958 | 4/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23395778 | 0.85 | ADAM10 (0.39) | NPY4RNPY1RFURINNPY2RNPY5R | |
| SCHEMBL25140406 | 0.77 | CTSS (0.42) | — | |
| SCHEMBL20029727 | 0.74 | FURIN (0.35) | NPY4RNPY1RFURINNPY2RNPY5R | |
| SCHEMBL21788077 | 0.69 | FURIN (0.38) | NPY4RNPY1RFURINNPY2RNPY5R | |
| SCHEMBL27352679 | 0.69 | FURIN (0.38) | NPY4RNPY1RFURINNPY2RNPY5R | |
| SCHEMBL23682482 | 0.69 | DPP4 (0.35) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL23917914 | 0.68 | FURIN (0.32) | FURIN | |
| SCHEMBL20159819 | 0.67 | FURIN (0.36) | NPY4RNPY1RFURINNPY2RNPY5R | |
| SCHEMBL20795891 | 0.67 | FURIN (0.36) | NPY4RNPY1RFURINNPY2RNPY5R | |
| SCHEMBL23736705 | 0.67 | FURIN (0.36) | NPY4RNPY1RFURINNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3521314-B1 | ANTIBODY-DRUG CONJUGATES AND USE THEREOF IN THERAPY | MC SAF (FR) | 2021-02-24 | — | — | EP | disclosed |