Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM10 | O14672 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | ADAM8 | P78325 | 2/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 6/20 | 0.33 |
| ▸ | FURIN | P09958 | 5/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.31 |
| ▸ | NPY4R | P50391 | 3/20 | 0.31 |
| ▸ | NPY1R | P25929 | 2/20 | 0.31 |
| ▸ | NPY2R | P49146 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23018211 | 0.85 | NPY4R (0.33) | ADAM10MMP2MMP9ADAM8ADAM17 | |
| SCHEMBL20029727 | 0.80 | FURIN (0.35) | ADAM10MMP2MMP9ADAM8ADAM17 | |
| SCHEMBL21233231 | 0.75 | DPP4 (0.40) | ADAM10MMP2MMP9ADAM8ADAM17 | |
| SCHEMBL23736705 | 0.74 | FURIN (0.36) | MMP9BMP1FURINC3AR1NPY4R | |
| SCHEMBL20795891 | 0.74 | FURIN (0.36) | MMP9BMP1FURINC3AR1NPY4R | |
| SCHEMBL20159819 | 0.74 | FURIN (0.36) | MMP9BMP1FURINC3AR1NPY4R | |
| SCHEMBL23236822 | 0.73 | BMP1 (0.36) | ADAM10MMP2MMP9ADAM8ADAM17 | |
| SCHEMBL21788077 | 0.73 | FURIN (0.38) | FURINC3AR1NPY4RNPY1RNPY2R | |
| SCHEMBL27352679 | 0.73 | FURIN (0.38) | FURINC3AR1NPY4RNPY1RNPY2R | |
| SCHEMBL23393940 | 0.72 | SIRT5 (0.39) | FURINC3AR1NPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3825304-A1 | ANTIBODY-DRUG CONJUGATES AND THE USE OF SAME IN THERAPY | Mc SAF (FR) | 2021-05-26 | — | — | EP | disclosed |