Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 2/20 | 0.35 |
| ▸ | TOP2A | P11388 | 2/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20144337 | 0.74 | NPBWR1 (0.44) | NPBWR1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7279599 | 0.68 | ALDH1A1 (0.51) | NPBWR1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL12347958 | 0.68 | NPC1 (0.68) | NPBWR1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL13533794 | 0.67 | NPC1 (0.60) | NPBWR1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL13528291 | 0.67 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL20144354 | 0.67 | HDAC3 (0.52) | — | |
| SCHEMBL21976216 | 0.66 | ALOX5 (0.65) | NPBWR1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL15445593 | 0.64 | MAOA (0.41) | NPBWR1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL19484925 | 0.64 | ALDH1A1 (0.63) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL14195881 | 0.64 | ADRB1 (0.50) | SMN1; SMN2ALDH1A1MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186247-B1 | PROTEIN KINASE INHIBITORS | ASTAR BIOTECH LLC (US) | 2021-03-03 | — | — | EP | disclosed |