SCHEMBL2308734

SCHEMBL2308734

C=CC(=O)N(C)C1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.44
PHGDH O43175 1/20 0.44
MGLL Q99685 1/20 0.44
ADH1C P00326 2/20 0.43
ADH1A P07327 2/20 0.43
ALDH1A1 P00352 4/20 0.43
ATM Q13315 1/20 0.41
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MAPK1 P28482 1/20 0.40
RAB9A P51151 4/20 0.39
NPC1 O15118 3/20 0.39
POLB P06746 3/20 0.36
ABCC1 P33527 1/20 0.36
BTK Q06187 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4086029 1.00 FAAH (0.44) FAAHPHGDHMGLLADH1CADH1A
SCHEMBL4076237 1.00 FAAH (0.44) FAAHPHGDHMGLLADH1CADH1A
SCHEMBL12198756 0.98 FAAH (0.41) FAAHPHGDHMGLLADH1CADH1A
SCHEMBL15710982 0.89
SCHEMBL23164467 0.83 BTK (0.35) FAAHPHGDHMGLLALDH1A1ATM
SCHEMBL15160517 0.82 JAK3 (0.35) BTK
SCHEMBL21251797 0.80 BCL2A1 (0.43) MEN1KMT2ARAB9ANPC1BTK
SCHEMBL2660134 0.79 ALDH1A1 (0.41) ALDH1A1KMT2ASMN1; SMN2POLBLMNA
SCHEMBL647829 0.78 TRPM8 (0.45) PHGDHADH1CADH1AALDH1A1TSHR
SCHEMBL12200666 0.78 MGLL (0.33) MGLLBTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110437944-A A kind of dedicated purificant of automatic dish-washing machine with resistive connection film and spotting performance GUANGZHOU LIBY ENTPR GROUP CO LTD 2019-11-12 CN claimed
CN-110373287-A A kind of automatic dish-washing machine cleansing tablet with heterogeneous structure 广州立白企业集团有限公司 2019-10-25 CN claimed
CN-107022048-B A kind of temperature sensitive driver of macromolecular and its preparation method and application 国家纳米科学中心 2019-02-22 CN claimed
CN-109055031-A A kind of automatic dish-washing machine special purpose detergent composition with resistive connection film and spotting effect 广州立白企业集团有限公司 2018-12-21 CN claimed
CN-107397959-A A kind of surface has the preparation method and application of the nanometer antagonist of ultra microstructure 国家纳米科学中心 2017-11-28 CN claimed
CN-107137724-A A kind of intracellular material for constructing temperature-responsive aggregation and its preparation method and application 国家纳米科学中心 2017-09-08 CN claimed
CN-107022048-A A kind of temperature sensitive driver of macromolecular and its preparation method and application 国家纳米科学中心 2017-08-08 CN claimed
CN-101213070-B Rapid replication process and radiation curable composition for use therein UNIV WIEN TECH 2012-06-27 CN claimed
US-7815835-B2 Rapid prototyping method and radiation-curable composition for use therein TECHNISCHE UNIVERSITAT WIEN (AT) 2010-10-19 US claimed
CN-1532566-B Radiation sensitive composition for color filter JSR CORP 2010-05-12 CN claimed
CN-101213070-A Rapid replication process and radiation curable composition for use therein UNIV WIEN TECH (AT) 2008-07-02 CN claimed
EP-1530600-B1 BIO-SYNTHETIC MATRIX AND USES THEREOF OTTAWA HEALTH RESEARCH INST (CA) 2007-03-14 EP claimed
US-20060134050-A1 Bio-synthetic matrix and uses thereof FORSKARPATENT I LINKOPING AB (SE) 2006-06-22 US claimed
US-20060034807-A1 Innervated artificial tissues and uses thereof OTTAWA HEALTH RESEARCH INSTITUTE 2006-02-16 US claimed
CN-1688622-A Bio-synthetic matrices and uses thereof OTTAWA HEALTH RESEARCH INST (CA) 2005-10-26 CN claimed
CN-1182166-C Heat resistant organic glass 北京大学 2004-12-29 CN claimed
CN-1314423-A Heat resistant organic glass UNIV BEIJING (CN) 2001-09-26 CN claimed
EP-0379305-B1 Low odor adhesive compositions MINNESOTA MINING & MFG (US) 1994-05-11 EP claimed
US-4945006-A UNSATURATED CYCLIC AMIDES, ANAEROBIC PROCESS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-07-31 US claimed
EP-0379305-A1 Low odor adhesive compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-07-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060034807-A1 Innervated artificial tissues and uses thereof NGF, GAP43, NTRK2 FAAH 419/4885PHGDH 737/4885MGLL 449/4885
US-20060134050-A1 Bio-synthetic matrix and uses thereof MMP1, HDGF, COL2A1 FAAH 3216/4885PHGDH 438/4885MGLL 1419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.