Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21474179 | 0.73 | GAA (0.39) | BRPF1NPC1TSHRALDH1A1GSK3B | |
| SCHEMBL23119712 | 0.71 | GAA (0.40) | NPC1TSHRALDH1A1GSK3BRAB9A | |
| SCHEMBL24405507 | 0.70 | PDE10A (0.37) | NPC1ALDH1A1GSK3BRAB9ASMN1; SMN2 | |
| SCHEMBL24405682 | 0.69 | PGR (0.36) | TSHRGSK3BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL24405634 | 0.69 | ALDH1A1 (0.40) | NPC1TSHRALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL21474157 | 0.68 | POLB (0.41) | TSHRALDH1A1GSK3BSMN1; SMN2MEN1 | |
| SCHEMBL21474041 | 0.68 | MCHR1 (0.38) | KCNJ5KCNJ3NPC1TSHRALDH1A1 | |
| SCHEMBL24405723 | 0.67 | GAA (0.39) | NPC1TSHRALDH1A1GSK3BRAB9A | |
| SCHEMBL24405558 | 0.67 | PGR (0.43) | NPC1ALDH1A1GSK3BRAB9AMEN1 | |
| SCHEMBL24405691 | 0.66 | CHRNB2 (0.47) | ALDH1A1GSK3BMTORPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11802120-B2 | Fused cyclic urea derivatives as CRHR2 antagonist | RAQUALIA PHARMA INC. (JP) | 2023-10-31 | — | — | US | disclosed |
| US-20210078975-A1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC. (JP) | 2021-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210078975-A1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | CRHR2, CRHR1, CRH | BRPF1 1565/4885KCNJ5 3971/4885KCNJ3 3693/4885 |
| US-11802120-B2 | Fused cyclic urea derivatives as CRHR2 antagonist | CRHR2, CRHR1, CRH | BRPF1 1565/4885KCNJ5 3971/4885KCNJ3 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.