Glycoursodeoxycholic Acid

Glycoursodeoxycholic Acid

SCHEMBL231609

C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 11/20 1.00
NR1H4 Q96RI1 6/20 1.00
ABCB11 O95342 5/20 1.00
ENPP2 Q13822 3/20 1.00
SLC10A2 Q12908 4/20 0.80
KMT2A Q03164 3/20 0.80
MEN1 O00255 2/20 0.80
LMNA P02545 1/20 0.80
CYP2C19 P33261 1/20 0.80
CHRM2 P08172 1/20 0.80
ADRA2A P08913 1/20 0.80
ADRA1A P35348 1/20 0.80
TDP1 Q9NUW8 1/20 0.80
SLC10A1 Q14973 1/20 0.80
CISD1 Q9NZ45 1/20 0.80
CYP3A4 P08684 1/20 0.80
VDR P11473 1/20 0.78
EPHA2 P29317 1/20 0.78
NR3C1 P04150 1/20 0.76
ABCC4 O15439 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycoursodeoxycholic Acid SCHEMBL20204267 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL13851608 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL11962429 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL28793575 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL9151495 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL12917601 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycochenodeoxycholate SCHEMBL236354 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL59881 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL935341 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL10694925 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1585 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146298-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS INTERNATIONAL N&H DENMARK APS (DK) 2026-05-28 US claimed
US-20260146992-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS INTERNATIONAL N&H DENMARK APS (DK) 2026-05-28 US claimed
CN-122075501-A Application of tauroursodeoxycholic acid in inhibiting alpha-glucosidase activity 2026-05-26 CN claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
CN-122017247-A Plasma metabolism marker for distinguishing benign thyroid diseases from early thyroid cancers and application of plasma metabolism marker 哈尔滨脉图精准技术有限公司 2026-05-12 CN claimed
CN-122017068-A Bile acid high-flux detection method based on ultra-high performance liquid chromatography tandem mass spectrometry and application thereof 青岛百谱生物科技有限公司 2026-05-12 CN claimed
EP-4721745-A1 COMBINED PRODUCT, SALT AND USE THEREOF Shanghai Henlius Biotech, Inc. (CN) 2026-04-08 EP claimed
EP-4721740-A1 COMBINATION PRODUCT, SALT, AND USE THEREOF IN TREATING NEURODEGENERATIVE DISEASES OR DISORDERS Shanghai Henlius Biotech, Inc. (CN) 2026-04-08 EP claimed
US-20260076959-A1 COMBINATION PRODUCT, SALT, AND USE THEREOF IN TREATING NEURODEGENERATIVE DISEASES OR DISORDERS SHANGHAI HENLIUS BIOTECH INC (CN) 2026-03-19 US claimed
US-20260078118-A1 COMBINED PRODUCT, SALT AND USE THEREOF SHANGHAI HENLIUS BIOTECH INC (CN) 2026-03-19 US claimed
US-6251428-B1 ADJUVANT, CARRIER YOO SEO HONG (US) 2001-06-26 US claimed
WO-2001012155-A1 COMPOSITIONS AND METHODS FOR ENHANCED ABSORPTION OF HYDROPHILIC THERAPEUTIC AGENTS LIPOCINE, INC. (US) 2001-02-22 WO claimed
WO-2001009163-A2 IMPROVEMENT OF PEPTIDE TRANSPORT BY CONJUGATION WITH BILE ACIDS THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 2001-02-08 WO claimed
WO-2001001960-A1 CLEAR OIL-CONTAINING PHARMACEUTICAL COMPOSITIONS LIPOCINE, INC. (US) 2001-01-11 WO claimed
WO-2000050007-A1 COMPOSITIONS AND METHODS FOR IMPROVED DELIVERY OF HYDROPHOBIC THERAPEUTIC AGENTS LIPOCINE, INC. (US) 2000-08-31 WO claimed
WO-2000004875-A2 PREPARATION OF AQUEOUS CLEAR SOLUTION DOSAGE FORMS WITH BILE ACIDS YOO SEO HONG (US) 2000-02-03 WO claimed
EP-0910411-A1 HYDROPHOBIC PREPARATIONS CONTAINING MEDIUM CHAIN MONOGLYCERIDES Cortecs (UK) Limited (GB) 1999-04-28 EP claimed
WO-1998000169-A1 HYDROPHOBIC PREPARATIONS CONTAINING MEDIUM CHAIN MONOGLYCERIDES CORTECS (UK) LIMITED) (GB) 1998-01-08 WO claimed
US-5616741-A Process for the preparation of glycine-conjugated bile acids ERREGIERRE INDUSTRIA CHIMICA S.P.A. (IT) 1997-04-01 US claimed
EP-0583566-A2 Process for the preparation of glycine-conjugated bile acids and relative pharmaceutical compositions useful for treating hepatic insufficiency ERREGIERRE INDUSTRIA CHIMICA Spa (IT) 1994-02-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146992-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS FABP2, AADAT, HNMT GPBAR1 105/4885NR1H4 1103/4885ABCB11 1527/4885
US-20260076959-A1 COMBINATION PRODUCT, SALT, AND USE THEREOF IN TREATING NEURODEGENERATIVE DISEASES OR DISORDERS SLC10A1, CYP46A1, CYP27A1 GPBAR1 4/4885NR1H4 6/4885ABCB11 22/4885
US-20260078118-A1 COMBINED PRODUCT, SALT AND USE THEREOF SLC10A1, SLC10A2, CYP27A1 GPBAR1 6/4885NR1H4 8/4885ABCB11 9/4885
US-20260146298-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS FABP2, SI, CSTB GPBAR1 2541/4885NR1H4 770/4885ABCB11 1821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.