Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.57 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.57 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 10/20 | 0.50 |
| ▸ | CNR2 | P34972 | 10/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543330 | 0.85 | GNAI3 (0.53) | GNAI3GNAO1GNAI1MEN1ALDH1A1 | |
| SCHEMBL1236493 | 0.85 | GNAI3 (0.50) | GNAI3GNAO1GNAI1MEN1ALDH1A1 | |
| SCHEMBL28340804 | 0.84 | GNAI3 (0.75) | GNAI3GNAO1GNAI1MEN1ALDH1A1 | |
| SCHEMBL1234276 | 0.84 | GNAI3 (0.75) | GNAI3GNAO1GNAI1MEN1ALDH1A1 | |
| SCHEMBL1457137 | 0.84 | GNAI3 (0.75) | GNAI3GNAO1GNAI1MEN1ALDH1A1 | |
| Hexadecanoic Acid Cyclopropylamide SCHEMBL1456457 | 0.84 | GNAI3 (0.75) | GNAI3GNAO1GNAI1MEN1ALDH1A1 | |
| SCHEMBL8361102 | 0.84 | GNAI3 (0.75) | GNAI3GNAO1GNAI1MEN1ALDH1A1 | |
| SCHEMBL11571826 | 0.84 | GNAI3 (0.75) | GNAI3GNAO1GNAI1MEN1ALDH1A1 | |
| SCHEMBL3551415 | 0.83 | GNAI3 (0.72) | GNAI3GNAO1GNAI1MEN1ALDH1A1 | |
| SCHEMBL13267848 | 0.82 | CYP1A2 (0.48) | GNAI3GNAO1GNAI1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189117-A1 | COSMETIC COMPOSITION CONTAINING A POLYORGANISILOXANE POLYMER | L'OREAL (FR) | 2011-08-04 | — | — | US | disclosed |
| US-7820146-B2 | Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form | L'OREAL S.A. (FR) | 2010-10-26 | — | — | US | disclosed |
| US-20080057011-A1 | Composition structured with a polymer containing a heteroatom and an Organogelator | L'OREAL S.A., | 2008-03-06 | — | — | US | disclosed |
| US-20050245673-A1 | Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form | L'OREAL S.A. (FR) | 2005-11-03 | — | — | US | disclosed |
| US-20050201961-A1 | Compositions containing a silicone resin film former and a silicone-containing copolymer | L'OREAL (FR) | 2005-09-15 | — | — | US | disclosed |
| US-20050158260-A1 | Cosmetic composition containing a polyorganosiloxane polymer | L'OREAL (FR) | 2005-07-21 | — | — | US | disclosed |
| US-20040223987-A1 | Composition structured with a polymer containing a heteroatom and organogelator | L'OREAL S.A. (FR) | 2004-11-11 | — | — | US | disclosed |
| US-6726915-B2 | DIAMIDE COMPOUNDS RETAINING GOOD COSMETIC PROPERTIES, IN PARTICULAR A CERTAIN LEVEL OF | L'OREAL (FR) | 2004-04-27 | — | — | US | disclosed |
| US-20030129211-A9 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | L'OREAL S.A. (FR) | 2003-07-10 | — | — | US | disclosed |
| US-20020150602-A1 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | LIVOREIL AUDE (FR) | 2002-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080057011-A1 | Composition structured with a polymer containing a heteroatom and an Organogelator | CUTA, FABP4, PARG | GNAI3 3467/4885GNAO1 4426/4885GNAI1 3638/4885 |
| US-20040223987-A1 | Composition structured with a polymer containing a heteroatom and organogelator | CUTA, PARG, FABP4 | GNAI3 3528/4885GNAO1 4473/4885GNAI1 3598/4885 |
| US-20030129211-A9 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | FAAH, HRH1, HRH4 | GNAI3 3751/4885GNAO1 3549/4885GNAI1 3336/4885 |
| US-20020150602-A1 | Cosmetic or pharmaceutical composition in solid form comprising bis-acyl-amides | FAAH, HRH1, HRH4 | GNAI3 3751/4885GNAO1 3549/4885GNAI1 3336/4885 |
| US-20050201961-A1 | Compositions containing a silicone resin film former and a silicone-containing copolymer | RAD51, SMURF1, RER1 | GNAI3 2610/4885GNAO1 3599/4885GNAI1 2366/4885 |
| US-20110189117-A1 | COSMETIC COMPOSITION CONTAINING A POLYORGANISILOXANE POLYMER | CUTA, PRDX1, PRXL2A | GNAI3 3591/4885GNAO1 2711/4885GNAI1 3407/4885 |
| US-20050158260-A1 | Cosmetic composition containing a polyorganosiloxane polymer | SQLE, CUTA, FDFT1 | GNAI3 3489/4885GNAO1 2652/4885GNAI1 3443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.