Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.44 |
| ▸ | NPC1 | O15118 | 10/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462546 | 0.88 | BACE1 (0.42) | RAB9ANPC1CYP3A4CYP1A2AR | |
| SCHEMBL15229223 | 0.82 | ALDH1A1 (0.43) | RAB9ANPC1CYP3A4ALDH1A1HPGD | |
| SCHEMBL2659111 | 0.79 | NPC1 (0.44) | RAB9ANPC1CYP1A2ALDH1A1HPGD | |
| SCHEMBL2320187 | 0.77 | KDM4E (0.47) | RAB9ANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6951103 | 0.76 | CYP1A2 (0.53) | RAB9ANPC1CYP3A4CYP1A2AR | |
| SCHEMBL628270 | 0.76 | ALDH1A1 (0.43) | RAB9ANPC1CYP1A2ALDH1A1HPGD | |
| SCHEMBL1217656 | 0.75 | GSTP1 (0.40) | RAB9ANPC1CYP1A2ARCYP2C9 | |
| SCHEMBL4099996 | 0.75 | ALDH1A1 (0.35) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL1542711 | 0.75 | DHODH (0.39) | RAB9ANPC1ALDH1A1HPGDMAPT | |
| SCHEMBL10394043 | 0.75 | MAPT (0.35) | RAB9ANPC1ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159464-A1 | PROCESS FOR PRODUCING 4,5-DIHYDRO-1H-PYRAZOLES AND INTERMEDIATES | NOVO NORDISK A/S (DK) | 2023-05-25 | — | — | US | disclosed |
| US-8298994-B2 | Substituted 1-(diazinyl)pyrazol-4-ylacetic acids, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2012-10-30 | — | — | US | disclosed |
| EP-2423190-A1 | Compounds Exhibiting PGD 2 Receptor Antagonism | Shionogi&Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-20120028995-A1 | NOVEL COMPOUNDS FOR MEDICAL USE AS PEPTIDASE EFFECTORS | IMTM GMBH (DE) | 2012-02-02 | — | — | US | disclosed |
| US-8067611-B2 | Substituted 1-(thiazolyl)-and 1-(isothiazolyl)pyrazol-4-ylacetic acids, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2011-11-29 | — | — | US | disclosed |
| US-20110257014-A1 | 1-(Heteroaryl)pyrazol-4-ylacetic acids, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2011-10-20 | — | — | US | disclosed |
| US-8017620-B2 | Dutpase inhibitors | MEDIVIR AB (SE) | 2011-09-13 | — | — | US | disclosed |
| US-20110117069-A1 | METHOD FOR ACTIVATING REGULATORY T-CELLS | IMTM GMBH (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20110021459-A1 | DUTPASE INHIBITORS | MEDIVIR AB (SE) | 2011-01-27 | — | — | US | disclosed |
| US-7795270-B2 | DUTPase inhibitors | MEDIVIR AB (SE) | 2010-09-14 | — | — | US | disclosed |
| WO-2005066160-A1 | DUTPASE INHIBITORS | MEDIVIR AB (SE) | 2005-07-21 | — | — | WO | disclosed |
| CN-1404480-A | Pyrimidine carboxamides as inhibitors of the PDE4 isozyme | PFIZER PROD INC (US) | 2003-03-19 | — | — | CN | disclosed |
| WO-2002069972-A2 | TRIAZOLE COMPOUNDS AND THE USE THEREOF IN THE PROPHYLAXIS AND THERAPY OF NEURODEGENERATIVE DISEASES, CEREBRAL TRAUMA AND CEREBRAL ISCHEMIA | ABBOTT GMBH & CO. KG (DE) | 2002-09-12 | — | — | WO | disclosed |
| US-RE37781-E1 | VIRICIDES, PROTEASE INHIBITOR | DUPONT PHARMACEUTICALS COMPANY | 2002-07-02 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| US-5514692-A | VIRICIDES | STERLING WINTHROP INC. (US) | 1996-05-07 | — | — | US | disclosed |
| US-5410052-A | Useful for extraction of ligand such as molecular oxygen from fluid environment and for release of such ligand | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-04-25 | — | — | US | disclosed |
| EP-0479892-A1 | FUSED-RING ARYL SUBSTITUTED IMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-15 | — | — | EP | disclosed |
| US-4959135-A | OXYGEN | AQUANAUTICS CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |
| WO-1988006641-A1 | POLYALKYLAMINE COMPLEXES FOR LIGAND EXTRACTION AND GENERATION | AQUANAUTICS CORPORATION (US) | 1988-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117069-A1 | METHOD FOR ACTIVATING REGULATORY T-CELLS | ANPEP, DNPEP, RNPEP | RAB9A 2409/4885NPC1 4377/4885CYP3A4 1761/4885 |
| US-20120028995-A1 | NOVEL COMPOUNDS FOR MEDICAL USE AS PEPTIDASE EFFECTORS | SERPINB1, CMA1, CPA3 | RAB9A 3465/4885NPC1 2884/4885CYP3A4 1304/4885 |
| US-20110021459-A1 | DUTPASE INHIBITORS | DUT, DHODH, NAT10 | RAB9A 3161/4885NPC1 1799/4885CYP3A4 1010/4885 |
| US-20110257014-A1 | 1-(Heteroaryl)pyrazol-4-ylacetic acids, processes for their preparation and their use as herbicides and plant growth regulators | DDT, HPD, DDC | RAB9A 2968/4885NPC1 4678/4885CYP3A4 563/4885 |
| US-20230159464-A1 | PROCESS FOR PRODUCING 4,5-DIHYDRO-1H-PYRAZOLES AND INTERMEDIATES | LMNB1, LMNB2, LMNA | RAB9A 1525/4885NPC1 693/4885CYP3A4 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.