Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB4 | P54760 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321685 | 0.82 | KIF11 (0.41) | KMO | |
| SCHEMBL2324956 | 0.79 | EPHB4 (0.46) | EPHB4TEKMEN1KMT2AKMO | |
| SCHEMBL2320060 | 0.78 | DEGS1 (0.45) | EPHB4TEKMEN1KMT2AKDM4E | |
| SCHEMBL2360453 | 0.78 | WNT3A (0.42) | EPHB4TEKMEN1KMT2AKDM4E | |
| SCHEMBL2320835 | 0.78 | FLT1 (0.44) | EPHB4TEKMEN1KMT2ARAB9A | |
| SCHEMBL24072334 | 0.77 | ABL1 (0.40) | EPHB4TEKRAB9AMAPTNPSR1 | |
| SCHEMBL2321384 | 0.77 | DEGS1 (0.41) | EPHB4TEKMEN1KMT2ARAB9A | |
| SCHEMBL2327132 | 0.73 | WNT3A (0.47) | TEKMEN1KMT2ARAB9ACYP11B2 | |
| SCHEMBL212774 | 0.73 | ACHE (0.45) | RAB9AALDH1A1NPC1 | |
| SCHEMBL20861444 | 0.73 | CRHR1 (0.35) | MEN1KMT2AKDM4ERAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |