Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860268 | 1.00 | RXRA (0.46) | RXRARXRBRXRGL3MBTL1ALDH1A1 | |
| SCHEMBL30741239 | 0.83 | CA12 (0.48) | L3MBTL1ALDH1A1TDP1KCNN4PTPN1 | |
| SCHEMBL3185351 | 0.83 | CA12 (0.48) | L3MBTL1ALDH1A1TDP1KCNN4PTPN1 | |
| SCHEMBL30741241 | 0.83 | CA12 (0.48) | L3MBTL1ALDH1A1TDP1KCNN4PTPN1 | |
| SCHEMBL3719912 | 0.82 | CLCN2 (0.36) | RXRARXRBRXRGL3MBTL1ALDH1A1 | |
| SCHEMBL18190386 | 0.82 | PTPN1 (0.35) | RXRARXRBRXRGL3MBTL1ALDH1A1 | |
| SCHEMBL29155199 | 0.81 | RXRA (0.44) | RXRARXRBRXRGL3MBTL1ALDH1A1 | |
| SCHEMBL10030738 | 0.81 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1SLC6A2SLC6A4SCN9A | |
| SCHEMBL3710628 | 0.80 | RXRA (0.35) | RXRARXRBRXRGL3MBTL1ALDH1A1 | |
| SCHEMBL29122166 | 0.79 | BACE1 (0.36) | RXRARXRBRXRGL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240140965-A1 | TRICYCLIC PESTICIDAL COMPOUNDS | BASF SE (DE) | 2024-05-02 | — | — | US | disclosed |
| EP-4305042-A1 | TRICYCLIC PESTICIDAL COMPOUNDS | BASF SE (DE) | 2024-01-17 | — | — | EP | disclosed |
| CN-116964062-A | Pesticidal tricyclic compounds | 巴斯夫欧洲公司 | 2023-10-27 | — | — | CN | disclosed |
| WO-2022189191-A1 | TRICYCLIC PESTICIDAL COMPOUNDS | BASF SE (DE) | 2022-09-15 | — | — | WO | disclosed |
| EP-2484669-B1 | PHENOL DERIVATIVES | FUJI YAKUHIN CO LTD (JP) | 2015-07-29 | — | — | EP | disclosed |
| CN-102639518-B | Novel Phenol Derivatives | FUJI YAKUHIN CO LTD | 2015-03-25 | — | — | CN | disclosed |
| US-8859584-B2 | TRPV1 antagonists | ABBVIE, INC. (US) | 2014-10-14 | — | — | US | disclosed |
| US-8609692-B2 | TRPV1 antagonists | ABBVIE INC. (US) | 2013-12-17 | — | — | US | disclosed |
| US-8604053-B2 | TRPV1 antagonists | ABBVIE INC. (US) | 2013-12-10 | — | — | US | disclosed |
| WO-2013096223-A1 | TRPV1 ANTAGONISTS | ABBVIE INC. (US) | 2013-06-27 | — | — | WO | disclosed |
| EP-2352726-A1 | TRPV1 ANTAGONISTS | Abbott Laboratories (US) | 2011-08-10 | — | — | EP | disclosed |
| EP-2352727-A1 | TRPV1 ANTAGONISTS | Abbott Laboratories (US) | 2011-08-10 | — | — | EP | disclosed |
| CN-101827585-A | Solid dispersion product containing N-aryl ureido compound | ABBOTT GMBH & CO KG | 2010-09-08 | — | — | CN | disclosed |
| EP-2197426-A2 | SOLID DISPERSION PRODUCT CONTAINING N-ARYL UREA-BASED COMPOUND | Abbott GmbH & Co. KG (DE) | 2010-06-23 | — | — | EP | disclosed |
| US-20100137360-A1 | TRPV1 ANTAGONISTS | ABBOTT LABORATORIES (US) | 2010-06-03 | — | — | US | disclosed |
| US-20100120846-A1 | TRPV1 ANTAGONISTS | ABBOTT LABORATORIES (US) | 2010-05-13 | — | — | US | disclosed |
| WO-2010045402-A1 | TRPV1 ANTAGONISTS | ABBOTT LABORATORIES (US) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010045401-A1 | TRPV1 ANTAGONISTS | ABBOTT LABORATORIES (US) | 2010-04-22 | — | — | WO | disclosed |
| US-20090143423-A1 | SOLID DISPERSION PRODUCT CONTAINING N-ARYL UREA-BASED COMPOUND | ABBOTT GMBH & CO. KG (DE) | 2009-06-04 | — | — | US | disclosed |
| WO-2009050289-A2 | SOLID DISPERSION PRODUCT CONTAINING N-ARYL UREA-BASED COMPOUND | ABBOTT GMBH & CO. KG (DE) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137360-A1 | TRPV1 ANTAGONISTS | TRPV1, TRPV3, TRPV2 | RXRA 494/4885RXRB 500/4885RXRG 453/4885 |
| US-20100120846-A1 | TRPV1 ANTAGONISTS | TRPV1, TRPV3, TRPV2 | RXRA 477/4885RXRB 478/4885RXRG 420/4885 |
| US-20240140965-A1 | TRICYCLIC PESTICIDAL COMPOUNDS | DDT, ACHE, PFAS | RXRA 4469/4885RXRB 4628/4885RXRG 4328/4885 |
| US-20090143423-A1 | SOLID DISPERSION PRODUCT CONTAINING N-ARYL UREA-BASED COMPOUND | U2SURP, UMPS, HNRNPUL1 | RXRA 1571/4885RXRB 1290/4885RXRG 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.