Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27811762 | 0.93 | NOTUM (0.57) | LMNANOTUMHTR6L3MBTL1ADORA1 | |
| SCHEMBL6190327 | 0.90 | CNR2 (0.50) | LMNANOTUMHTR6L3MBTL1ADORA1 | |
| SCHEMBL8387356 | 0.88 | HTR6 (0.57) | LMNANOTUMHTR6L3MBTL1ADORA1 | |
| SCHEMBL3792311 | 0.85 | KDM4E (0.52) | LMNAL3MBTL1NPSR1HTTCYP1A2 | |
| SCHEMBL701030 | 0.84 | NR4A2 (0.53) | LMNAHTR6L3MBTL1ADORA1NPSR1 | |
| SCHEMBL31668281 | 0.81 | HDAC1 (0.51) | LMNAHTR6L3MBTL1ADORA1NPSR1 | |
| Hydrochloric Acid SCHEMBL7881899 | 0.81 | HTR6 (0.47) | LMNAHTR6L3MBTL1ADORA1NPSR1 | |
| SCHEMBL5761906 | 0.81 | CYP19A1 (0.51) | LMNANOTUML3MBTL1CNR2CNR1 | |
| SCHEMBL1606606 | 0.81 | LMNA (0.80) | LMNAL3MBTL1ADORA1NPSR1CNR2 | |
| SCHEMBL21818692 | 0.79 | MCL1 (0.47) | LMNANPSR1CNR2HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243160-A1 | INDOLE DERIVATIVES FOR TARGETING AUTOPHAGY | Automera PTE. LTD (SG) | 2025-07-31 | — | — | US | disclosed |
| US-20220127266-A1 | MALIC ENZYME INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2022-04-28 | — | — | US | disclosed |
| US-11225480-B2 | Malic enzyme inhibitors | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2022-01-18 | — | — | US | disclosed |
| US-20210115038-A1 | MALIC ENZYME INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2021-04-22 | — | — | US | disclosed |
| CN-110003169-A | GPR40 receptor agonist, method for preparing same, and pharmaceutical composition containing same as active ingredient | 株式会社LG化学 | 2019-07-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115038-A1 | MALIC ENZYME INHIBITORS | ME1, ME2, ME3 | LMNA 4129/4885NOTUM 365/4885HTR6 4816/4885 |
| US-11225480-B2 | Malic enzyme inhibitors | ME1, RNASE1, ME2 | LMNA 3853/4885NOTUM 783/4885HTR6 4870/4885 |
| US-20220127266-A1 | MALIC ENZYME INHIBITORS | ME1, ME2, ME3 | LMNA 4129/4885NOTUM 365/4885HTR6 4816/4885 |
| US-20250243160-A1 | INDOLE DERIVATIVES FOR TARGETING AUTOPHAGY | SQSTM1, ATG7, BECN1 | LMNA 1131/4885NOTUM 4719/4885HTR6 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.