Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521742 | 0.74 | HTT (0.45) | POLB | |
| SCHEMBL23245054 | 0.72 | THRA (0.61) | THRATHRB | |
| SCHEMBL16130822 | 0.71 | PKM (0.33) | POLBP2RX3 | |
| SCHEMBL24449323 | 0.64 | HSP90AA1 (0.34) | NPSR1THRATHRB | |
| SCHEMBL24449325 | 0.64 | GRIA1 (0.39) | THRATHRB | |
| SCHEMBL38650588 | 0.63 | NPBWR1 (0.37) | POLBNPSR1 | |
| SCHEMBL29488647 | 0.62 | THRA (0.32) | THRATHRB | |
| SCHEMBL21846831 | 0.62 | CRBN (0.34) | POLB | |
| SCHEMBL4490436 | 0.62 | POLB (0.32) | POLB | |
| SCHEMBL23028988 | 0.60 | POLB (0.32) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210115022-A1 | THYROID HORMONE RECEPTOR AGONISTS AND USES THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115022-A1 | THYROID HORMONE RECEPTOR AGONISTS AND USES THEREOF | TSHR, THRA, TRHR | POLB 3496/4885NPSR1 89/4885P2RX3 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.