Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25464806 | 0.91 | KCNH2 (0.49) | KCNH2MAPTALOX15L3MBTL1RAB9A | |
| SCHEMBL28543421 | 0.90 | ALDH1A1 (0.48) | KCNH2MAPTALOX15L3MBTL1RAB9A | |
| SCHEMBL23319914 | 0.89 | HTR3E (0.48) | KCNH2MAPTALOX15L3MBTL1ALDH1A1 | |
| SCHEMBL23319950 | 0.89 | PKM (0.47) | MAPTALOX15L3MBTL1ALDH1A1PKM | |
| SCHEMBL28546887 | 0.85 | MAPT (0.56) | MAPTALOX15L3MBTL1ALDH1A1PKM | |
| SCHEMBL23319902 | 0.82 | MEN1 (0.60) | MAPTALOX15L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25463546 | 0.82 | ALOX15 (0.51) | MAPTALOX15L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL22816438 | 0.81 | SMN1; SMN2 (0.46) | MAPTALOX15L3MBTL1ALDH1A1PKM | |
| SCHEMBL22816039 | 0.80 | SMN1; SMN2 (0.46) | MAPTALOX15L3MBTL1ALDH1A1PKM | |
| SCHEMBL22816026 | 0.79 | ALDH1A1 (0.45) | KCNH2MAPTALOX15L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112399873-B | Triazole glycolate oxidase inhibitors | 坎特罗治疗有限公司 | 2024-10-25 | — | — | CN | disclosed |
| US-20230143491-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | PHOENIX TISSUE REPAIR, INC. | 2023-05-11 | — | — | US | disclosed |
| US-11401246-B2 | Triazole glycolate oxidase inhibitors | Cantero Therapeutics, Inc. (US) | 2022-08-02 | — | — | US | disclosed |
| US-20210403439-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | VENTHERA, INC. | 2021-12-30 | — | — | US | disclosed |
| EP-3817816-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | Orfan Biotech Inc. (US) | 2021-05-12 | — | — | EP | disclosed |
| CN-112399873-A | Triazole glycolate oxidase inhibitor | 奥凡生物科技公司 | 2021-02-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11401246-B2 | Triazole glycolate oxidase inhibitors | XDH, DUOX1, PNPO | KCNH2 2775/4885MAPT 1718/4885ALOX15 71/4885 |
| US-20230143491-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | XDH, DUOX1, PNPO | KCNH2 2775/4885MAPT 1718/4885ALOX15 71/4885 |
| US-20210403439-A1 | TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | XDH, DUOX1, PNPO | KCNH2 2775/4885MAPT 1718/4885ALOX15 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.