Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD5 | P21918 | 9/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 5/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21470913 | 0.82 | ESR2 (0.43) | ABHD6ESR2PDK2 | |
| SCHEMBL21470914 | 0.79 | SLC6A2 (0.44) | DRD5 | |
| SCHEMBL29238589 | 0.77 | ESR2 (0.49) | ABHD6ESR1ESR2KIF11 | |
| SCHEMBL29238643 | 0.72 | KIF11 (0.49) | ABHD6ESR1ESR2KIF11 | |
| SCHEMBL13886242 | 0.71 | ABHD6 (0.59) | ABHD6PDK2 | |
| SCHEMBL23327090 | 0.70 | CA1 (0.45) | ESR1ESR2 | |
| SCHEMBL29118083 | 0.69 | HTR5A (0.48) | — | |
| SCHEMBL3356388 | 0.66 | RBP4 (0.38) | — | |
| SCHEMBL23327030 | 0.66 | PDK2 (0.34) | ESR1ESR2PDK2 | |
| SCHEMBL12313602 | 0.66 | RYR2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139484-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | GOSSAMER BIO SERVICES INC (US) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139484-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ULK1, PHKG2, PHKG1 | DRD5 4798/4885ABHD6 3806/4885ESR1 1230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.