Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.37 |
| ▸ | GABRP | O00591 | 4/20 | 0.37 |
| ▸ | GABRD | O14764 | 4/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.37 |
| ▸ | GABRE | P78334 | 4/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20579147 | 0.81 | KDM4E (0.37) | CTSSNOTUMGABRA1GABRB2KDM4E | |
| SCHEMBL561772 | 0.79 | ALDH1A1 (0.40) | TACR1SLC6A4KCNH2GABRB3GABRP | |
| SCHEMBL31297895 | 0.78 | CTSS (0.42) | CTSSMBOAT4TACR1SLC6A4KCNH2 | |
| SCHEMBL2336311 | 0.78 | CTSS (0.42) | CTSSMBOAT4TACR1SLC6A4KCNH2 | |
| SCHEMBL29331705 | 0.77 | AR (0.43) | CTSSSLC6A4KCNH2KDM4EALDH1A1 | |
| SCHEMBL2336364 | 0.77 | MBOAT4 (0.42) | CTSSMBOAT4TACR1SLC6A4KCNH2 | |
| SCHEMBL19837606 | 0.77 | CTSS (0.41) | CTSSMBOAT4TACR1SLC6A4KCNH2 | |
| SCHEMBL29349713 | 0.77 | MBOAT4 (0.42) | CTSSMBOAT4TACR1SLC6A4KCNH2 | |
| SCHEMBL28046956 | 0.77 | MBOAT4 (0.42) | CTSSMBOAT4TACR1SLC6A4KCNH2 | |
| SCHEMBL19837476 | 0.77 | CTSS (0.39) | CTSSMBOAT4TACR1SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4486453-A1 | BENZAMIDE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2025-01-08 | — | — | EP | disclosed |
| CN-119241408-A | Trifluoro methyl sulfide molecule as HIF2a inhibitor | 维眸生物科技(浙江)有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-118843616-A | Benzamide compounds for the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2024-10-25 | — | — | CN | disclosed |
| WO-2023166103-A1 | BENZAMIDE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-09-07 | — | — | WO | disclosed |
| US-RE49446-E1 | Oxadiazolopyridine derivatives for use as ghrelin O-acyl transferase (GOAT) inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-03-07 | — | — | US | disclosed |
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | AMGEN INC. (US) | 2023-02-07 | — | — | US | disclosed |
| CN-109843891-B | Oxadiazolopyridine derivatives as ghrelin O-acyltransferase (GOAT) inhibitors | 勃林格殷格翰国际有限公司 | 2021-11-23 | — | — | CN | disclosed |
| EP-3494120-B1 | OXADIAZOLOPYRIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2021-03-17 | — | — | EP | disclosed |
| EP-3494120-B1 | OXADIAZOLOPYRIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2021-03-17 | — | — | EP | disclosed |
| EP-3494120-A1 | OXADIAZOLOPYRIDINE DERIVATES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2019-06-12 | — | — | EP | disclosed |
| US-8318776-B2 | Pyridine compound, pesticidal composition and method of controlling pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-11-27 | — | — | US | disclosed |
| US-8318776-B2 | Pyridine compound, pesticidal composition and method of controlling pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-11-27 | — | — | US | disclosed |
| EP-2215086-B1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL CO (JP) | 2011-08-24 | — | — | EP | disclosed |
| EP-2215086-B1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL CO (JP) | 2011-08-24 | — | — | EP | disclosed |
| US-20100286148-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286148-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286148-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-2215086-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | Sumitomo Chemical Company, Limited (JP) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009066786-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066786-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | CYP3A7, CYP51A1, NT5C3B | CTSS 3158/4885NOTUM 473/4885MBOAT4 3362/4885 |
| US-20100286148-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | C5, PRDX1, PLPBP | CTSS 1059/4885NOTUM 1449/4885MBOAT4 4694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.