Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18199915 | 0.78 | CCR1 (0.50) | NOS3NOS1NOS2PDE10ACCR1 | |
| SCHEMBL18682147 | 0.74 | PDE10A (0.58) | PDE10A | |
| SCHEMBL13458731 | 0.73 | CCR1 (0.56) | CCR1 | |
| SCHEMBL19413635 | 0.71 | NOS3 (0.41) | S1PR1NOS3NOS1NOS2KDM4E | |
| SCHEMBL6970064 | 0.70 | TUBB4A (0.34) | CCR1KDM4E | |
| SCHEMBL6970068 | 0.70 | MCHR1 (0.37) | S1PR1CCR1KDM4E | |
| SCHEMBL15865602 | 0.67 | METAP2 (0.53) | PDE10AKDM4EHPGDHSD17B10 | |
| SCHEMBL14768504 | 0.66 | LMNA (0.59) | PDE10ACCR1KDM4EHPGD | |
| SCHEMBL13037327 | 0.65 | KDM4E (0.46) | CCR1KDM4E | |
| SCHEMBL9210740 | 0.65 | PDE3A (0.41) | PDE10ACCR1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008290-B2 | Halogenated quinoline derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11008290-B2 | Halogenated quinoline derivatives as antimicrobial agents | NDUFS5, NDUFS7, NDUFS3 | S1PR1 4787/4885NOS3 310/4885NOS1 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.