Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 6/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | VEGFA | P15692 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | GALR1 | P47211 | 1/20 | 0.31 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2351722 | 0.90 | MAOA (0.35) | GRIA2ADRA1D | |
| SCHEMBL2357565 | 0.88 | GRIA2 (0.43) | GRIA2ADRA1DGALR1SLC10A2 | |
| SCHEMBL2353940 | 0.86 | GRIA2 (0.48) | GRIA2SMN1; SMN2ADRA1DKDM4EPGR | |
| SCHEMBL2353968 | 0.85 | GRIA2 (0.47) | GRIA2SLC6A2SLC6A4SLC6A3ADRA1D | |
| SCHEMBL2353944 | 0.83 | GRIA2 (0.44) | GRIA2SMN1; SMN2ADRA1DSLC10A2 | |
| SCHEMBL2357699 | 0.82 | CA1 (0.35) | GALR1 | |
| SCHEMBL2352846 | 0.82 | ADRA1D (0.42) | GRIA2SLC6A2SLC6A4SLC6A3ADRA1D | |
| SCHEMBL2353218 | 0.80 | ADRA1D (0.46) | GRIA2ADRA1DKDM4EGALR1SLC10A2 | |
| SCHEMBL2354007 | 0.73 | MMP2 (0.46) | SMN1; SMN2ADRA1D | |
| SCHEMBL2355589 | 0.71 | ADRA1D (0.40) | GRIA2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | claimed |
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | disclosed |