Tiliroside

Tiliroside

SCHEMBL23597

O=C(/C=C/c1ccc(O)cc1)OC[C@H]1O[C@@H](Oc2c(-c3ccc(O)cc3)oc3cc(O)cc(O)c3c2=O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 1.00
CA4 P22748 5/20 1.00
CA7 P43166 5/20 1.00
CYP3A4 P08684 2/20 1.00
TYR P14679 1/20 1.00
CA2 P00918 4/20 0.86
AKR1B1 P15121 3/20 0.84
P4HB P07237 4/20 0.70
ACHE P22303 1/20 0.70
RPS6KA3 P51812 3/20 0.69
POLB P06746 3/20 0.67
GAA P10253 3/20 0.67
APEX1 P27695 2/20 0.67
RECQL P46063 2/20 0.67
XDH P47989 2/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
CBS P35520 1/20 0.66
NQO2 P16083 1/20 0.62
KDM4E B2RXH2 2/20 0.62
ADRA2C P18825 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tiliroside SCHEMBL28142584 1.00 CA12 (1.00) CA12CA4CA7CYP3A4TYR
Tiliroside SCHEMBL12568488 1.00 CA12 (1.00) CA12CA4CA7CYP3A4TYR
Tiliroside SCHEMBL29366630 1.00 CA12 (1.00) CA12CA4CA7CYP3A4TYR
Tiliroside SCHEMBL23598 1.00 CA12 (1.00) CA12CA4CA7CYP3A4TYR
Tiliroside SCHEMBL13963382 1.00 CA12 (1.00) CA12CA4CA7CYP3A4TYR
Tiliroside SCHEMBL16131015 1.00 CA12 (1.00) CA12CA4CA7CYP3A4TYR
Tiliroside SCHEMBL31082442 1.00 CA12 (1.00) CA12CA4CA7CYP3A4TYR
Tiliroside SCHEMBL12568460 1.00 CA12 (1.00) CA12CA4CA7CYP3A4TYR
Tiliroside SCHEMBL15756208 1.00 CA12 (1.00) CA12CA4CA7CYP3A4TYR
SCHEMBL18922182 0.96 CA12 (0.93) CA12CA4CA7CYP3A4TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 549 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743181-A1 POLYPHENOL-RICH DAMASK ROSE EXTRACT DERIVED FROM A HYDRODISTILLATION BYPRODUCT AND ITS USES AS A FOOD SUPPLEMENT Robertet S.A. (FR) 2026-05-20 EP claimed
US-12419317-B1 Plant derived food preservative IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-09-23 US claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
CN-120189494-A Use of adiponectin and adiponectin receptor agonists for the treatment of amyotrophic lateral sclerosis 河北医科大学第二医院 2025-06-24 CN claimed
CN-119949504-A China hemp peptide nutrition protein powder and preparation method thereof 天之草健康科技(长沙)有限公司 2025-05-09 CN claimed
CN-119335091-A High performance liquid chromatography detection method for simultaneously measuring 14 polyphenols 劲牌有限公司 2025-01-21 CN claimed
WO-2025011789-A1 POLYPHENOL-RICH DAMASK ROSE EXTRACT DERIVED FROM A HYDRODISTILLATION BYPRODUCT AND ITS USES AS A FOOD SUPPLEMENT ROBERTET S.A. (FR) 2025-01-16 WO claimed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 WO claimed
CN-117084979-B Preparation and application of pickering multiple emulsion with stable phytosterol/chitosan composite particles 江南大学 2024-12-06 CN claimed
CN-118903174-A Application of tiliroside in preparation of medicines for treating atherosclerosis 西南医科大学附属医院 2024-11-08 CN claimed
US-20080193569-A1 Extraction Method for Producing Plant Extracts, Especially Waltheria Paniculata Extracts Containing Tiliroside MERCK PATENT GESELLSCHAFT (DE) 2008-08-14 US claimed
US-20080044502-A1 USE OF AN AQUEOUS OR HYDROALCOHOLIC EXTRACT OF BAUHINIA FOR THE PREPARATION OF A COMPOSITION WIRTH CORINNA 2008-02-21 US claimed
EP-1363594-B1 COSMETIC FORMULATIONS CONTAINING FLAVONOID DERIVATIVES MERCK PATENT GMBH (DE) 2007-11-21 EP claimed
EP-1393733-B1 Use of flavonoid-derivatives for the treatment of atopic eczema MERCK PATENT GMBH (DE) 2006-08-23 EP claimed
US-20050019426-A1 For care, protection from aging of skin and hair, use in treatment of various skin disorders such as leukoplakia, eczema, keratosis, psoriasis, or to promote wound healing MERCK PATENT GMBH (DE) 2005-01-27 US claimed
US-20040081675-A1 Cosmetic formulations containing flavonoid derivatives MERCK PATENT GMBH (DE) 2004-04-29 US claimed
US-20040053860-A1 Flavonoid derivatives for the treatment of eczema MERCK PATENT GMBH (DE) 2004-03-18 US claimed
EP-1393733-A1 Flavonoid-derivate for the treatment of eczema MERCK PATENT GmbH (DE) 2004-03-03 EP claimed
US-6471973-B2 DRUGS, COSMETICS, DIETETICS, AGRICULTURE COLETICA (FR) 2002-10-29 US claimed
US-20010031735-A1 Flavonoide esters and their use notably in cosmetics COLETICA (FR) 2001-10-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031735-A1 Flavonoide esters and their use notably in cosmetics TYR, MITF, CYP2F1 CA12 1957/4885CA4 948/4885CA7 932/4885
US-20040081675-A1 Cosmetic formulations containing flavonoid derivatives TYR, MITF, TEAD3 CA12 4880/4885CA4 4790/4885CA7 4827/4885
US-20040053860-A1 Flavonoid derivatives for the treatment of eczema TSLP, CYP51A1, TYR CA12 4787/4885CA4 4516/4885CA7 4491/4885
US-20050019426-A1 For care, protection from aging of skin and hair, use in treatment of various skin disorders such as leukoplakia, eczema, keratosis, psoriasis, or to promote wound healing ITCH, CUTA, POLR1C CA12 4407/4885CA4 3659/4885CA7 3419/4885
US-20080193569-A1 Extraction Method for Producing Plant Extracts, Especially Waltheria Paniculata Extracts Containing Tiliroside MITF, FZD7, LSS CA12 3680/4885CA4 2108/4885CA7 1373/4885
US-20080044502-A1 USE OF AN AQUEOUS OR HYDROALCOHOLIC EXTRACT OF BAUHINIA FOR THE PREPARATION OF A COMPOSITION BROX, HAAO, HIRA CA12 2398/4885CA4 1551/4885CA7 1036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.