Indocyanine Green Acid Form

Indocyanine Green Acid Form

SCHEMBL23630

CC1(C)C(/C=C/C=C/C=C/C=C2\N(CCCCS(=O)(=O)[O-])c3ccc4ccccc4c3C2(C)C)=[N+](CCCCS(=O)(=O)[O-])c2ccc3ccccc3c21.[Na+]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Indocyanine Green Acid Form. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 known ✓ P0DMS8 1/20 0.91
ADORA1 known ✓ P30542 1/20 0.91
PTGS2 known ✓ P35354 1/20 0.91
PDE4D known ✓ Q08499 1/20 0.91
PDE3A known ✓ Q14432 1/20 0.91
THRB known ✓ P10828 1/20 0.42
PPARG known ✓ P37231 1/20 0.42
BLM P54132 2/20 1.00
HRH3 Q9Y5N1 2/20 0.91
MLNR O43193 1/20 0.91
NR1I2 O75469 1/20 0.91
PGR P06401 1/20 0.91
ADRB1 P08588 1/20 0.91
CHRM1 P11229 1/20 0.91
DRD2 P14416 1/20 0.91
ADRA2B P18089 1/20 0.91
ADRA2C P18825 1/20 0.91
CHRM3 P20309 1/20 0.91
CNR1 P21554 1/20 0.91
DRD1 P21728 1/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indocyanine Green Acid Form SCHEMBL29379095 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
Indocyanine Green Acid Form SCHEMBL30292068 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
Indocyanine Green Acid Form SCHEMBL29474196 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
Indocyanine Green Acid Form SCHEMBL335877 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
SCHEMBL19859088 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
Indocyanine Green Acid Form SCHEMBL29374051 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
Indocyanine Green Acid Form SCHEMBL16027582 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
Indocyanine Green Acid Form SCHEMBL23631 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
SCHEMBL20097450 0.96 BLM (0.93) BLMHRH3MLNRNR1I2PGR
SCHEMBL25610661 0.96 BLM (0.93) BLMHRH3MLNRNR1I2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 34444 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746925-A1 USES OF TRIGLYCERIDE AND PHOSPHOLIPID COMPOSITIONS SonoClear AS (NO) 2026-05-27 EP claimed
EP-3993771-B1 SONODYNAMIC THERAPY INNOVATION ULSTER LTD (GB) 2026-05-27 EP claimed
EP-4748304-A2 SYSTEM AND METHOD FOR IDENTIFYING BLOOD VESSELS DURING FLUORESCENCE IMAGING Perfusion Tech ApS (DK) 2026-05-27 EP claimed
CN-117011232-B Method and device for testing quality detection of fluorescent image and electronic equipment Zhuhai Dipu Medical Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
US-12636383-B2 Methods of applying preparations of dyes and hydrogels to a tissue KORCZYKOWSKI, Marc (US) 2026-05-26 US claimed
US-12635877-B2 Methods and systems for quantifying retinal vascular patterns and treatment of disease OHIO STATE INNOVATION FOUNDATION (US) 2026-05-26 US claimed
CN-122075726-A Wasp venom peptide-M nano-composite and preparation method and application thereof 2026-05-26 CN claimed
CN-120859949-B Composite nano-particles of targeted mesenchymal stem cells and application thereof in preparation of medicines for promoting vascularization bone regeneration BEIJING STOMATOLOGICAL HOSPITAL, CAPITAL MEDICAL UNIVERSITY (CN) 2026-05-26 CN claimed
US-20260137558-A1 OPHTHALMIC DEVICE Able Tx Ltd. (IL) 2026-05-21 US claimed
WO-2026107170-A1 OPTICAL CLEARING OF TISSUES AND ORGANS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-05-21 WO claimed
EP-0374190-A4 SPECTROPHOTOMETRIC METHOD FOR QUANTITATIVELY DETERMINING THE CONCENTRATION OF A DILUTE COMPONENT IN A LIGHT- OR OTHER RADIATION-SCATTERING ENVIRONMENT 1991-07-31 EP claimed
WO-1991004073-A1 LASER TISSUE WELDING WITH DYE ENHANCED SOLDERS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1991-04-04 WO claimed
EP-0374190-A1 SPECTROPHOTOMETRIC METHOD FOR QUANTITATIVELY DETERMINING THE CONCENTRATION OF A DILUTE COMPONENT IN A LIGHT- OR OTHER RADIATION-SCATTERING ENVIRONMENT. VANDER CORP (US) 1990-06-27 EP claimed
EP-0165630-B1 METHOD OF PREPARING A CHLORINATED, BROMINATED, RADIOBROMINATED, IODINATED AND/OR RADIOIODINATED, AROMATIC OR HETEROAROMATIC COMPOUND, AS WELL AS A KIT FOR PREPARING A DIAGNOSTIC COMPOSITION ON THE BASIS OF THIS COMPOUND MALLINCKRODT, INC.(a Missouri corporation) (US) 1989-10-18 EP claimed
US-4874949-A Method of measuring lung vascular function and transcapillary transport by the use of nonradioactive markers VANDERBILT UNIVERSITY (US) 1989-10-17 US claimed
WO-1989001758-A1 SPECTROPHOTOMETRIC METHOD FOR QUANTITATIVELY DETERMINING THE CONCENTRATION OF A DILUTE COMPONENT IN A LIGHT- OR OTHER RADIATION-SCATTERING ENVIRONMENT VANDER CORPORATION (US) 1989-03-09 WO claimed
US-4805623-A Spectrophotometric method for quantitatively determining the concentration of a dilute component in a light- or other radiation-scattering environment VANDER CORPORATION (US) 1989-02-21 US claimed
US-4639745-A Optical recording medium PIONEER ELECTRONIC CORPORATION (JP) 1987-01-27 US claimed
EP-0165630-A2 Method of preparing a chlorinated, brominated, radiobrominated, iodinated and/or radioiodinated, aromatic or heteroaromatic compound, as well as a kit for preparing a diagnostic composition on the basis of this compound MALLINCKRODT, INC.(a Missouri corporation) (US) 1985-12-27 EP claimed
US-3959455-A Labeling of indocyanine green with carrier-free iodine-123 THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES ENERGY RESEARCH AND DEVELOPMENT ADMINISTRATION (US) 1976-05-25 US claimed