Indocyanine Green Acid Form

Indocyanine Green Acid Form

SCHEMBL335877

CC1(C)C(C=CC=C/C=C/C=C2/N(CCCCS(=O)(=O)[O-])c3ccc4ccccc4c3C2(C)C)=[N+](CCCCS(=O)(=O)[O-])c2ccc3ccccc3c21.[Na+]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

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Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Indocyanine Green Acid Form. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 known ✓ P0DMS8 1/20 0.91
ADORA1 known ✓ P30542 1/20 0.91
PTGS2 known ✓ P35354 1/20 0.91
PDE4D known ✓ Q08499 1/20 0.91
PDE3A known ✓ Q14432 1/20 0.91
THRB known ✓ P10828 1/20 0.42
PPARG known ✓ P37231 1/20 0.42
BLM P54132 2/20 1.00
HRH3 Q9Y5N1 2/20 0.91
MLNR O43193 1/20 0.91
NR1I2 O75469 1/20 0.91
PGR P06401 1/20 0.91
ADRB1 P08588 1/20 0.91
CHRM1 P11229 1/20 0.91
DRD2 P14416 1/20 0.91
ADRA2B P18089 1/20 0.91
ADRA2C P18825 1/20 0.91
CHRM3 P20309 1/20 0.91
CNR1 P21554 1/20 0.91
DRD1 P21728 1/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indocyanine Green Acid Form SCHEMBL29379095 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
Indocyanine Green Acid Form SCHEMBL30292068 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
Indocyanine Green Acid Form SCHEMBL29474196 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
SCHEMBL19859088 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
Indocyanine Green Acid Form SCHEMBL23630 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
Indocyanine Green Acid Form SCHEMBL29374051 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
Indocyanine Green Acid Form SCHEMBL16027582 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
Indocyanine Green Acid Form SCHEMBL23631 1.00 BLM (1.00) BLMHRH3MLNRNR1I2PGR
SCHEMBL20097450 0.96 BLM (0.93) BLMHRH3MLNRNR1I2PGR
SCHEMBL25610661 0.96 BLM (0.93) BLMHRH3MLNRNR1I2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110100268-B Method for disinfection and disinfection quality control of a user's hand and device for carrying out the method 手扫描股份有限公司 2021-07-27 CN claimed
US-10977926-B2 Method for the disinfection and the quality control of the disinfection of the hands of a user and apparatus for carrying out the method HANDINSCAN ZRT. (HU) 2021-04-13 US claimed
EP-3555869-A1 METHOD FOR THE DISINFECTION AND THE QUALITY CONTROL OF THE DISINFECTION OF THE HANDS OF A USER AND APPARATUS FOR CARRYING OUT THE METHOD HandinScan Zrt. (HU) 2019-10-23 EP claimed
CN-110100268-A The method of disinfection and the sterilisation quality's control of hand for user and the equipment for executing this method 手扫描股份有限公司 2019-08-06 CN claimed
US-20190172336-A1 Method for the disinfection and the quality control of the disinfection of the hands of a user and apparatus for carrying out the method HANDINSCAN ZRT. (HU) 2019-06-06 US claimed
US-20110244390-A1 DONOR ELEMENT WITH MALEIC ANHYDRIDE BASED POLYMERS FOR THERMAL TRANSFER E. I. DU PONT DE NEMOURS AND COMPANY 2011-10-06 US claimed
EP-1805037-B1 DONOR ELEMENT WITH RELEASE-MODIFIER FOR THERMAL TRANSFER DU PONT (US) 2011-10-05 EP claimed
CN-101437691-B Donor element with maleic anhydride based polymers for thermal transfer DU PONT 2011-10-05 CN claimed
JP-4713592-B2 2011-06-29 JP claimed
CN-101044031-B Donor element and its preparation method, method for imaging donor element DU PONT 2011-04-06 CN claimed
US-7387864-B2 Donor element for thermal transfer E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-06-17 US claimed
US-20080003519-A1 Donor Element for Thermal Transfer E. I. DU PONT DE NEMOURS AND COMPANY 2008-01-03 US claimed
WO-2007124001-A2 DONOR ELEMENT WITH MALEIC ANHYDRIDE BASED POLYMERS FOR THERMAL TRANSFER E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-01 WO claimed
CN-101044031-A Donor element with release-modifier for thermal transfer DU PONT (US) 2007-09-26 CN claimed
CN-101044032-A Donor element for thermal transfer DU PONT (US) 2007-09-26 CN claimed
EP-1805037-A1 DONOR ELEMENT WITH RELEASE-MODIFIER FOR THERMAL TRANSFER E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-07-11 EP claimed
EP-1805034-A1 DONOR ELEMENT FOR THERMAL TRANSFER E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-07-11 EP claimed
WO-2006045084-A1 DONOR ELEMENT WITH RELEASE-MODIFIER FOR THERMAL TRANSFER E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-04-27 WO claimed
WO-2006045085-A1 DONOR ELEMENT FOR THERMAL TRANSFER E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-04-27 WO claimed
EP-0743523-B1 Dye-based reference material, preparation and use thereof BAYER AG (US) 2002-08-28 EP claimed