Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.39 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 4/20 | 0.36 |
| ▸ | TACR1 | P25103 | 4/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177725 | 0.87 | NNMT (0.53) | NNMTLMNAMKNK1MKNK2KMT2A | |
| SCHEMBL29730575 | 0.87 | NNMT (0.53) | NNMTLMNAMKNK1MKNK2KMT2A | |
| SCHEMBL26633645 | 0.85 | GPR119 (0.48) | NNMT | |
| SCHEMBL31158308 | 0.85 | GPR119 (0.48) | NNMT | |
| SCHEMBL3662100 | 0.83 | LMNA (0.43) | NNMTLMNAKCNH2NPY1RSLC6A4 | |
| SCHEMBL23647537 | 0.81 | HSD11B1 (0.41) | KCNH2NPY1RSLC6A4TET3KMT2A | |
| SCHEMBL23647376 | 0.80 | KMT2A (0.59) | LMNATET3KMT2AFBXL19CXXC5 | |
| SCHEMBL2790975 | 0.79 | ALDH1A1 (0.40) | NNMTLMNAKCNH2NPY1RSLC6A4 | |
| SCHEMBL3258917 | 0.77 | NNMT (0.46) | NNMTLMNAMKNK1MKNK2TET3 | |
| SCHEMBL23112352 | 0.75 | NNMT (0.42) | NNMTLMNAKCNH2MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143680-A1 | HETEROARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2021-07-22 | — | — | WO | disclosed |