Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.50 |
| ▸ | ADH1B | P00325 | 2/20 | 0.50 |
| ▸ | ADH1C | P00326 | 2/20 | 0.50 |
| ▸ | ADH1A | P07327 | 2/20 | 0.50 |
| ▸ | ADH7 | P40394 | 2/20 | 0.50 |
| ▸ | ADH4 | P08319 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1566984 | 1.00 | EPHX1 (0.50) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL8931323 | 0.98 | EPHX1 (0.54) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL3277867 | 0.98 | EPHX1 (0.54) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL3278556 | 0.98 | EPHX1 (0.54) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL3278822 | 0.98 | EPHX1 (0.54) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL3283014 | 0.94 | ADH1B (0.48) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL3279314 | 0.85 | — | — | |
| SCHEMBL9580783 | 0.82 | EPHX1 (0.48) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL28178568 | 0.82 | EPHX1 (0.54) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL1005048 | 0.80 | HCAR2 (0.42) | EPHX1ADH1BADH1CADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214813-B2 | Preparation of chiral cyclic amino acids and derivatives | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-05-08 | — | — | US | claimed |
| US-20040242889-A1 | Preparation of chiral cyclic amino acids and derivatives | THE PENN STATE RESEARCH FOUNDATION | 2004-12-02 | — | — | US | claimed |
| WO-2004011414-A1 | E-ISOMERIC β-AROMATIC OR HETEROAROMATIC SUBSTITUTED β-ACYLAMINO-ACRYLATES AND METHODS OF PREPARING THE SAME | DSM IP ASSETS B.V. (NL) | 2004-02-05 | — | — | WO | claimed |
| US-7994355-B2 | Metallocene-based chiral phosphine or arsine ligands | SOLVIAS AG (CH) | 2011-08-09 | — | — | US | disclosed |
| EP-1844061-B1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | SOLVIAS AG (CH) | 2010-08-04 | — | — | EP | disclosed |
| EP-1709054-B1 | METALLOCENE-BASED CHIRAL PHOSPHINE OR ARSINE LIGANDS | PHOENIX CHEMICALS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| EP-1725570-B1 | PROCESS FOR THE PRODUCTION OF ASYMMETRIC TRANSFORMATION CATALYSTS | PHOENIX CHEMICALS LTD (GB) | 2008-08-13 | — | — | EP | disclosed |
| EP-1844061-A1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | Phoenix Chemicals Limited (GB) | 2007-10-17 | — | — | EP | disclosed |
| US-20070161762-A1 | Metallocene-based chiral phosphine or arsine ligands | PHOENIX CHEMICALS LIMITED (GB) | 2007-07-12 | — | — | US | disclosed |
| US-7214813-B2 | Preparation of chiral cyclic amino acids and derivatives | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-05-08 | — | — | US | disclosed |
| US-7169953-B2 | P-chiral phospholanes and phosphocyclic compounds and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-01-30 | — | — | US | disclosed |
| US-20050119495-A1 | P-chiral phospholanes and phosphocyclic compounds and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION | 2005-06-02 | — | — | US | disclosed |
| US-20050014633-A1 | Biphenyldiphosphine compounds | HONG KONG POLYTECHNIC UNIVERSITY, THE (HK) | 2005-01-20 | — | — | US | disclosed |
| US-20040242889-A1 | Preparation of chiral cyclic amino acids and derivatives | THE PENN STATE RESEARCH FOUNDATION | 2004-12-02 | — | — | US | disclosed |
| US-20040229846-A1 | P-chiral phospholanes and phosphocyclic compounds and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION | 2004-11-18 | — | — | US | disclosed |
| WO-2004011414-A1 | E-ISOMERIC β-AROMATIC OR HETEROAROMATIC SUBSTITUTED β-ACYLAMINO-ACRYLATES AND METHODS OF PREPARING THE SAME | DSM IP ASSETS B.V. (NL) | 2004-02-05 | — | — | WO | disclosed |
| WO-2004011414-A1 | E-ISOMERIC β-AROMATIC OR HETEROAROMATIC SUBSTITUTED β-ACYLAMINO-ACRYLATES AND METHODS OF PREPARING THE SAME | DSM IP ASSETS B.V. (NL) | 2004-02-05 | — | — | WO | disclosed |
| EP-0117252-B1 | AMINO-POLYOL DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-06-24 | — | — | EP | disclosed |
| US-4501909-A | CHEMICAL INTERMEDIATES IN THE SYNTHESIS OF AMINO SUGARS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1985-02-26 | — | — | US | disclosed |
| EP-0117252-A1 | AMINO-POLYOL DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1984-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229846-A1 | P-chiral phospholanes and phosphocyclic compounds and their use in asymmetric catalytic reactions | PNKP, PFKFB4, PFKFB3 | EPHX1 504/4885ADH1B 1410/4885ADH1C 440/4885 |
| US-20050014633-A1 | Biphenyldiphosphine compounds | INPP5B, PCBP1, ITPA | EPHX1 1643/4885ADH1B 1871/4885ADH1C 3402/4885 |
| US-20040242889-A1 | Preparation of chiral cyclic amino acids and derivatives | AADAT, PAM, BCAT2 | EPHX1 4177/4885ADH1B 3524/4885ADH1C 3571/4885 |
| US-20070161762-A1 | Metallocene-based chiral phosphine or arsine ligands | OSGEP, PHOSPHO1, ITPA | EPHX1 3577/4885ADH1B 3785/4885ADH1C 3980/4885 |
| US-20050119495-A1 | P-chiral phospholanes and phosphocyclic compounds and their use in asymmetric catalytic reactions | PFKFB4, PFKFB3, PFKFB1 | EPHX1 426/4885ADH1B 993/4885ADH1C 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.