SCHEMBL2369731

SCHEMBL2369731

CC(C)(C)Oc1ccc(CN)cc1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ST14 Q9Y5Y6 1/20 0.50
MAOB P27338 9/20 0.46
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
HRH3 Q9Y5N1 1/20 0.44
LOXL2 Q9Y4K0 4/20 0.42
ABAT P80404 1/20 0.41
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12239025 0.94 ST14 (0.61) ST14MAOBKEAP1NFE2L2HRH3
SCHEMBL29673211 0.85 ST14 (0.45) ST14MAOBKEAP1NFE2L2HRH3
SCHEMBL1049645 0.83 TAAR1 (0.61) MAOBTAAR1
SCHEMBL30967134 0.83 MAOB (0.47) ST14MAOBKEAP1NFE2L2HRH3
SCHEMBL197077 0.81 ELANE (0.50) PPARGPPARA
Hydrochloric Acid SCHEMBL14157305 0.81 TAAR1 (0.59) MAOBTAAR1
SCHEMBL26746 0.80 SLC6A2 (0.44) PPARGPPARA
SCHEMBL19015929 0.79 SLC6A4 (0.63) TAAR1
SCHEMBL507215 0.79 MAOB (0.45) ST14MAOBKEAP1NFE2L2HRH3
SCHEMBL18266508 0.79 ST14 (0.48) ST14MAOBKEAP1NFE2L2HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0064702-B1 4-TERT.-BUTOXYBENZYL AMINES BASF Aktiengesellschaft (DE) 1984-05-02 EP claimed
EP-0064702-A1 4-Tert.-butoxybenzyl amines BASF Aktiengesellschaft (DE) 1982-11-17 EP claimed
EP-4635568-A2 COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES ACADIA Pharmaceuticals Inc. (US) 2025-10-22 EP disclosed
EP-4622966-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-10-01 EP disclosed
EP-3672954-B1 COMPOUNDS, SALTS THEREOF AND THEIR USE FOR THE TREATMENT OF DISEASES ACADIA PHARM INC (US) 2025-08-13 EP disclosed
US-20250213735-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2025-07-03 US disclosed
US-20250197385-A1 COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES ACADIA PHARM INC (US) 2025-06-19 US disclosed
CN-116354923-B Nitrogen-containing heterocyclic compound and application thereof 江苏恩华药业股份有限公司 2025-05-09 CN disclosed
US-20250032573-A1 IMMUNITY-ENHANCING PEPTIDE ANALOGS AND USES THEREOF Research & Business Foundation Sungkyunkwan University (KR) 2025-01-30 US disclosed
US-12139477-B2 Compounds, salts thereof and methods for treatment of diseases ACADIA PHARMACEUTICALS INC. (US) 2024-11-12 US disclosed
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
US-20070167426-A1 Compounds for the treatment of inflammatory disorders and microbial diseases SCHERING CORPORATION 2007-07-19 US disclosed
US-7244849-B2 Process for preparing a thiazole PPAR-ligand and polymorphs thereof GLAXO GROUP LIMITED (GB) 2007-07-17 US disclosed
US-20070129378-A1 Compounds for the treatment of inflammatory disorders and microbial diseases SCHERING CORPORATION 2007-06-07 US disclosed
US-20060178366-A1 Compounds for the treatment of inflammatory disorders SCHERING CORPORATION 2006-08-10 US disclosed
EP-0064702-B1 4-TERT.-BUTOXYBENZYL AMINES BASF Aktiengesellschaft (DE) 1984-05-02 EP disclosed
EP-0064702-B1 4-TERT.-BUTOXYBENZYL AMINES BASF Aktiengesellschaft (DE) 1984-05-02 EP disclosed
EP-0064702-A1 4-Tert.-butoxybenzyl amines BASF Aktiengesellschaft (DE) 1982-11-17 EP disclosed
EP-0064702-A1 4-Tert.-butoxybenzyl amines BASF Aktiengesellschaft (DE) 1982-11-17 EP disclosed
EP-0064702-A1 4-Tert.-butoxybenzyl amines BASF Aktiengesellschaft (DE) 1982-11-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070167426-A1 Compounds for the treatment of inflammatory disorders and microbial diseases MMP12, ADAMTS1, ADAM33 ST14 1293/4885MAOB 1390/4885KEAP1 1256/4885
US-12139477-B2 Compounds, salts thereof and methods for treatment of diseases SLC10A1, CYP27A1, CYP11B2 ST14 2999/4885MAOB 459/4885KEAP1 426/4885
US-20250213735-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R ST14 2171/4885MAOB 773/4885KEAP1 4210/4885
US-20060178366-A1 Compounds for the treatment of inflammatory disorders MMP12, ADAMTS1, TNF ST14 1344/4885MAOB 1341/4885KEAP1 1379/4885
US-20250197385-A1 COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES SLC10A1, CYP27A1, CYP11B2 ST14 2999/4885MAOB 459/4885KEAP1 426/4885
US-20070129378-A1 Compounds for the treatment of inflammatory disorders and microbial diseases MMP12, PCSK9, ALPI ST14 834/4885MAOB 1191/4885KEAP1 1679/4885
US-20250032573-A1 IMMUNITY-ENHANCING PEPTIDE ANALOGS AND USES THEREOF FPR3, FPR1, FPR2 ST14 1049/4885MAOB 3805/4885KEAP1 2927/4885
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R ST14 2171/4885MAOB 773/4885KEAP1 4210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.