Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 5/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 6/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2372547 | 0.87 | DHODH (0.54) | PLA2G2ANOTUMDHODHKDM4EGAA | |
| SCHEMBL2372472 | 0.85 | PLA2G2A (0.51) | PLA2G2ADHODHKDM4EALDH1A1GAA | |
| SCHEMBL2372690 | 0.79 | TRPV4 (0.51) | — | |
| SCHEMBL2373216 | 0.77 | LMNA (0.51) | PLA2G2ADHODHKDM4ECYP2C9 | |
| SCHEMBL2373306 | 0.76 | DHODH (0.51) | PLA2G2ADHODHKDM4EALDH1A1CYP2C9 | |
| SCHEMBL2373281 | 0.74 | KDM4E (0.55) | PLA2G2ADHODHKDM4EALDH1A1 | |
| SCHEMBL2372172 | 0.73 | PLA2G2A (0.51) | PLA2G2ADHODHSCDKDRKDM4E | |
| SCHEMBL2373699 | 0.73 | CTSA (0.44) | RORBMRGPRX4ALDH1A1GAA | |
| SCHEMBL2372142 | 0.73 | CTSA (0.44) | RORBMRGPRX4ALDH1A1GAA | |
| SCHEMBL2373864 | 0.73 | DHODH (0.54) | DHODHKDM4EALDH1A1GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |