Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770724 | 0.88 | MAP4K1 (0.34) | CCNT1TYK2MAP4K1 | |
| SCHEMBL23770741 | 0.88 | ABL1 (0.35) | CCNT1MAP4K1 | |
| SCHEMBL23770489 | 0.84 | HSD11B1 (0.33) | CCNT1MAP4K1 | |
| SCHEMBL23770850 | 0.80 | LRRK2 (0.33) | — | |
| SCHEMBL23770455 | 0.79 | CCNT1 (0.32) | CCNT1 | |
| SCHEMBL23770822 | 0.79 | MPL (0.33) | CCNT1TYK2 | |
| SCHEMBL23770669 | 0.74 | HTR3A (0.40) | CCNT1 | |
| SCHEMBL23770808 | 0.74 | HTR3E (0.38) | CCNT1 | |
| SCHEMBL23770836 | 0.74 | MPL (0.33) | — | |
| SCHEMBL23770753 | 0.73 | GRIN2B (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |