Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.40 |
| ▸ | HTR3B | O95264 | 2/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 5/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770632 | 0.90 | ADRB2 (0.42) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL23770808 | 0.90 | HTR3E (0.38) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL23770819 | 0.86 | HTR3A (0.41) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL23770724 | 0.85 | MAP4K1 (0.34) | CCNT1CDK9MAPK14SCN9A | |
| SCHEMBL23770455 | 0.85 | CCNT1 (0.32) | CCNT1CDK9MAPK14SCN9A | |
| SCHEMBL23770731 | 0.84 | HTR3A (0.40) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL23770862 | 0.83 | HTR3E (0.42) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL23770868 | 0.83 | PTPN11 (0.37) | PTPN11KCNH2HTR1A | |
| SCHEMBL23770661 | 0.81 | HTR3A (0.39) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL23770475 | 0.80 | L3MBTL1 (0.39) | ALDH1A1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |