Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770808 | 0.85 | HTR3E (0.38) | ABL1PTPN11 | |
| SCHEMBL23770508 | 0.85 | ABL1 (0.35) | ABL1SMOPTPN11 | |
| SCHEMBL23770741 | 0.81 | ABL1 (0.35) | ABL1SMO | |
| SCHEMBL23770831 | 0.80 | ABL1 (0.33) | ABL1 | |
| SCHEMBL23770446 | 0.80 | SUV39H2 (0.39) | SMO | |
| SCHEMBL23770754 | 0.80 | ABL1 (0.31) | ABL1 | |
| SCHEMBL23770868 | 0.80 | PTPN11 (0.37) | ABL1PTPN11 | |
| SCHEMBL23770558 | 0.76 | AGPAT2 (0.40) | ABL1 | |
| SCHEMBL23770685 | 0.76 | ABL1 (0.37) | ABL1 | |
| SCHEMBL23770669 | 0.75 | HTR3A (0.40) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |