Triaziquone

Triaziquone

SCHEMBL2377783

C=C[SiH2]OCCOC.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
STAT3 P40763 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
DNMT1 P26358 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL5081824 0.79 TP53 (0.36) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL9798617 0.78 DNMT1 (0.33) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL7715400 0.75 TP53 (0.35) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL6763730 0.74 DNMT1 (0.42) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL8935221 0.74 TP53 (0.34) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL8607425 0.73 DNMT1 (0.41) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL9651053 0.73 DNMT1 (0.41) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL8303 0.72 DNMT1 (0.48) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL610295 0.71 DNMT1 (0.42) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL21358774 0.71 MAPT (0.43) TP53MAPTSTAT3HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6881288-B2 Method of making a reinforcing mat for a pultruded part PELLA CORPORATION (US) 2005-04-19 US claimed
US-20020123287-A1 Reinforcing mat for a pultruded part PELLA CORPORATION 2002-09-05 US claimed
US-20020121722-A1 Method of making a pultruded part with a reinforcing mat PELLA CORPORATION 2002-09-05 US claimed
US-20020123288-A1 Pultruded part with reinforcing mat PELLA CORPORATION 2002-09-05 US claimed
US-20020121720-A1 Method of making a reinforcing mat for a pultruded part PELLA CORPORATION 2002-09-05 US claimed
EP-3335689-B1 DENTAL COMPOSITION DENTSPLY DETREY GMBH (DE) 2025-03-19 EP disclosed
US-12023392-B2 Additive manufacturing process DENTSPLY SIRONA INC. (US) 2024-07-02 US disclosed
US-20240180791-A1 DENTAL COMPOSITION DENTSPLY SIRONA INC. (US) 2024-06-06 US disclosed
US-11931432-B2 Dental composition DENTSPLY SIRONA INC. (US) 2024-03-19 US disclosed
US-11918664-B2 Direct dental filling compositions DENTSPLY SIRONA INC. (US) 2024-03-05 US disclosed
US-11904030-B2 Dental composition DENTSPLY SIRONA INC. (US) 2024-02-20 US disclosed
US-11883510-B2 Dental composition comprising a particulate carrier supporting a coinitiator DENTSPLY SIRONA INC. (US) 2024-01-30 US disclosed
WO-2003049928-A1 REINFORCING MAT FOR A PULTRUDED PART PELLA CORPORATION (US) 2003-06-19 WO disclosed
US-20020123287-A1 Reinforcing mat for a pultruded part PELLA CORPORATION 2002-09-05 US disclosed
US-20020121722-A1 Method of making a pultruded part with a reinforcing mat PELLA CORPORATION 2002-09-05 US disclosed
US-20020123288-A1 Pultruded part with reinforcing mat PELLA CORPORATION 2002-09-05 US disclosed
US-20020121720-A1 Method of making a reinforcing mat for a pultruded part PELLA CORPORATION 2002-09-05 US disclosed
EP-1172424-A1 PRIMER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2002-01-16 EP disclosed
EP-0838097-A1 ELECTROCATALYTIC STRUCTURE COMPRISING A MATRIX OF SiOxCyHz HAVING DISPERSED THEREIN PARTICLES OF CATALYTIC MATERIAL THE DOW CHEMICAL COMPANY (US) 1998-04-29 EP disclosed
WO-1997003476-A1 ELECTROCATALYTIC STRUCTURE COMPRISING A MATRIX OF SiOxCyHz HAVING DISPERSED THEREIN PARTICLES OF CATALYTIC MATERIAL THE DOW CHEMICAL COMPANY (US) 1997-01-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240180791-A1 DENTAL COMPOSITION CAD, MTR, ESD TP53 3083/4885MAPT 822/4885STAT3 2784/4885
US-11904030-B2 Dental composition CBR3, CBR1, PRDX3 TP53 4267/4885MAPT 1727/4885STAT3 1581/4885
US-11931432-B2 Dental composition CAD, MTR, ESD TP53 3083/4885MAPT 822/4885STAT3 2784/4885
US-12023392-B2 Additive manufacturing process FLNA, FLNB, SAMM50 TP53 2035/4885MAPT 1152/4885STAT3 4336/4885
US-11883510-B2 Dental composition comprising a particulate carrier supporting a coinitiator PICALM, PDS5B, CLTA TP53 846/4885MAPT 557/4885STAT3 4765/4885
US-11918664-B2 Direct dental filling compositions CAD, DOCK5, ITGA5 TP53 86/4885MAPT 810/4885STAT3 4069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.