Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23794891 | 0.80 | MAPK10 (0.50) | RAB9APOLBNPC1MEN1KMT2A | |
| SCHEMBL5788078 | 0.80 | RAB9A (0.43) | RAB9APOLBNPC1RAPGEF4MEN1 | |
| SCHEMBL23794894 | 0.80 | AURKA (0.49) | RAB9APOLBNPC1MEN1KMT2A | |
| SCHEMBL23794893 | 0.80 | MAPT (0.48) | RAB9APOLBHPGDNPC1MEN1 | |
| SCHEMBL23794897 | 0.79 | ROCK1 (0.51) | RAB9APOLBNPC1MEN1KMT2A | |
| SCHEMBL23794896 | 0.79 | RAB9A (0.59) | RAB9APOLBNPC1MEN1KMT2A | |
| SCHEMBL5765529 | 0.79 | KMT2A (0.50) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL23794892 | 0.76 | KMT2A (0.48) | KMT2A | |
| SCHEMBL5801454 | 0.73 | CA1 (0.47) | BACE1BACE2 | |
| SCHEMBL18086470 | 0.72 | RAB9A (0.60) | RAB9AHAO1HPGDNPC1RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876933-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | Chang Gung University of Science and Technology (TW) | 2021-09-15 | — | — | EP | disclosed |