Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23794894 | 0.80 | AURKA (0.49) | MEN1KMT2ALMNARAB9ANPC1 | |
| SCHEMBL5788078 | 0.80 | RAB9A (0.43) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL23794887 | 0.80 | RAB9A (0.60) | MEN1KMT2ALMNARAB9AMAPK1 | |
| SCHEMBL23794893 | 0.80 | MAPT (0.48) | MEN1KMT2ALMNARAB9AMAPK1 | |
| SCHEMBL23794892 | 0.79 | KMT2A (0.48) | KMT2AKCNH2SCN5ASCN9A | |
| SCHEMBL5765529 | 0.79 | KMT2A (0.50) | MEN1KMT2ARAB9AMAPK1NPC1 | |
| SCHEMBL23794896 | 0.76 | RAB9A (0.59) | MEN1KMT2ALMNARAB9AMAPK1 | |
| SCHEMBL23794897 | 0.76 | ROCK1 (0.51) | MEN1KMT2ARAB9AMAPK1NPC1 | |
| SCHEMBL24938165 | 0.72 | SMN1; SMN2 (0.36) | KMT2ARAB9AMAPK1NPC1MAPT | |
| SCHEMBL5801454 | 0.70 | CA1 (0.47) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876933-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | Chang Gung University of Science and Technology (TW) | 2021-09-15 | — | — | EP | disclosed |