Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23794887 | 0.79 | RAB9A (0.60) | RAB9ANPC1MAPTTP53SMN1; SMN2 | |
| SCHEMBL5788078 | 0.76 | RAB9A (0.43) | RAB9ANPC1MAPTSMN1; SMN2HTT | |
| SCHEMBL23794894 | 0.76 | AURKA (0.49) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23794891 | 0.76 | MAPK10 (0.50) | RAB9ANPC1MAPTTP53SMN1; SMN2 | |
| SCHEMBL23794893 | 0.76 | MAPT (0.48) | RAB9ANPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL23794896 | 0.75 | RAB9A (0.59) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5765529 | 0.75 | KMT2A (0.50) | ROCK1RAB9ANPC1MAPTTP53 | |
| SCHEMBL23918534 | 0.73 | KDM1A (0.52) | ROCK1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL23794892 | 0.71 | KMT2A (0.48) | KMT2A | |
| SCHEMBL5801454 | 0.69 | CA1 (0.47) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876933-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | Chang Gung University of Science and Technology (TW) | 2021-09-15 | — | — | EP | disclosed |